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JNJ-5207852
SynDRA canonical compound SYN0004557 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | HRH3 |
|---|
| Mechanism of action | histamine receptor antagonist |
|---|
| Indication | epilepsy |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Mechanisms of action (all sources)
- HRH3 ANTAGONIST
- histamine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- ADGRF1
- S1PR1
- RAD52
- OGG1
- NEIL2
- NEIL1
- HRH4
- HRH2
- HRH1
- GPR35
- GPR119
- GLP1R
- FPR2
- FFAR4
- CX3CR1
- C5AR1
- APLNR
- AGTR1
- ADRB2
- ADRA2A
- TDG
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- COMT
- GAMT
- GNMT
- HNMT
- M4K2
- NNMT
- PNMT
Cross-references
Synonyms
- JNJ 5207852
- UNII-4I9OVB1G7D
- 1-[4-(3-piperidinopropoxy)benzyl]piperidine
- 4I9OVB1G7D
- CHEMBL129542
- JNJ 5207852 dihydrochloride
- 1-[3-[4-(piperidin-1-ylmethyl)phenoxy]propyl]piperidine
- Piperidine, 1-(3-(4-(1-piperidinylmethyl)phenoxy)propyl)-
- 1-(3-(4-((Piperidin-1-yl)methyl)phenoxy)propyl)piperidine
- 1-(3-(4-(piperidin-1-ylmethyl)phenoxy)propyl)piperidine
- Piperidine, 1-[3-[4-(1-piperidinylmethyl)phenoxy]propyl]-
- 1-(3-{4-[(piperidin-1-yl)methyl]phenoxy}propyl)piperidine
- AC1MCCJO
- 1-[3-[4-(1-piperidinylmethyl)phenoxy]propyl]piperidine
- 1-(3-(4-(1-Piperidinylmethyl)phenoxy)propyl)piperidine
- RefChem:907271
- DTXCID70328607
- 1-(4-(3-(piperidin-1-yl)propoxy)benzyl)piperidine
- MFCD05974930
- JNJ5207852
- UNII-4I9OVB1G7D;
- MLS001166116
- 1-[3-[4-(1-piperidylmethyl)phenoxy]propyl]piperidine
- GTPL1256
- orb1299842
- SCHEMBL3577334
- C20H32N2O
- EX-A763
- PTKHFRNHJULJKT-UHFFFAOYSA-N
- HMS2852B03
- BDBM50159110
- AKOS005076686
- NCGC00371012-01
- AC-36816
- DA-59759
- HY-12190
- JNJ-5207852?
- SMR000550361
- CS-0003148
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