← SynDRA

JNJ-7777120

SynDRA canonical compound SYN0004555 — structure-anchored drug synonym record

All known targets

• HRH4

Mechanisms of action (all sources)

• HRH4 ANTAGONIST
• histamine receptor antagonist

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• HRH1
• HRH2
• HRH3
• CYP2C9
• CYP2D6
• CYP3A4
• HDAC6

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• GP183
• KSYK
• SYK

Cross-references

• PubChem CID: 4908365
• ChEMBL: CHEMBL129198
• Wikipedia: JNJ-7777120
• TTD: D0E9SR

Synonyms

• [3H]JNJ 7777120
• 1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine
• JNJ 7777120
• JNJ7777120
• UNII-4H1AU2V37X
• HUQJRYMLJBBEDO-UHFFFAOYSA-N
• 4H1AU2V37X
• CHEMBL129198
• 1-[(5-CHLORO-1H-INDOL-2-YL)CARBONYL]-4-METHYL-PIPERAZINE
• 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine
• (5-chloro-1H-indol-2-yl)-(4-methylpiperazin-1-yl)methanone
• (5-chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone
• METHANONE, (5-CHLORO-1H-INDOL-2-YL)(4-METHYL-1-PIPERAZINYL)-
• STK175446
• [3H]-JNJ7777120
• 1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine
• RefChem:403912
• (5-Chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)methanone
• (5-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone
• MFCD04343337
• 5-CHLORO-2-(4-METHYLPIPERAZINE-1-CARBONYL)-1H-INDOLE
• SCHEMBL186434
• GTPL1278
• GTPL1279
• orb1306004
• SCHEMBL29381532
• BDBM22566
• HMS3651L08
• HMS3884L22
• HMS5223J03
• EX-A2082
• EBC-80304
• s2905
• AKOS005410426
• CCG-267222
• CS-4964
• ES-0048
• SB19527