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BUTAMBEN
SynDRA canonical compound SYN0004528 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Mechanism of action | sodium channel blocker |
|---|
All known targets
Mechanisms of action (all sources)
- TRPV4 INHIBITOR
- Transient receptor potential cation channel subfamily V member 4 inhibitor
- TRPA1 INHIBITOR
- Transient receptor potential cation channel subfamily A member 1 inhibitor
- sodium channel blocker
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- ESR2
- ESR1
- MAOA
- NPY2R
- NPY1R
- NFE2L2
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- ACHE
- NR3C1
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- LMNA
- OPRD1
- HDAC6
- OPRK1
- TSHR
- TBXAS1
- TBXA2R
- TARDBP
- TACR2
- TACR1
- SLCO1B3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- AHR
- ANDR
- CP1A2
- CP2C9
- CP2CJ
- CP3A4
- CP3A7
- ESRRA
- IF4H
- PABP1
- PRGR
- RARA
Drug classes
- Anesthetics
- Anesthetics, Local
- Central Nervous System Agents
- Central Nervous System Depressants
- Peripheral Nervous System Agents
- Sensory System Agents
Cross-references
Synonyms
- butambene
- butesin
- butesine
- butoform
- butyl 4-aminobenzoate
- butylcaine
- Butyl aminobenzoate
- Butyl p-aminobenzoate
- Butyl paba
- P-aminobenzoic acid butyl ester
- ABBOTT-34842 FREE BASE
- NSC-128464
- Butesin
- butyl -4-aminobenzoate
- Butoform
- Butylcaine
- Butesine
- Planoform
- Scuroform
- Scuroforme
- BUTYL P-AMINOBENZOATE
- 4-(Butoxycarbonyl)aniline
- Butyl keloform
- Benzoic acid, 4-amino-, butyl ester
- n-Butyl-p-aminobenzoate
- p-Aminobenzoic acid butyl ester
- 4-Aminobenzoic acid butyl ester
- 4-Aminobenzoic Acid n-Butyl Ester
- Butyl PABA
- Benzoic acid, p-amino-, butyl ester
- MFCD00017112
- 4-amino butylbenzoate
- p-Aminobenzoic acid, butyl ester
- Butylester kyseliny p-aminobenzoove
- 4-Aminobenzoic acid butyl
- MLS000028721
- CHEBI:3231
- EFW857872Q
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