← SynDRA
PRAMOXINE
SynDRA canonical compound SYN0004505 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | topical anesthetic |
|---|
| Indication | corticosteroid-responsive dermatoses |
|---|
| Disease area | dermatology |
|---|
All known targets
- Pgrmc1
- SCN1A
- SCN2A
- SCN3A
- SIGMAR1
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HRH3
- HTR2B
- DRD3
- KCNH2
- CHRM2
- ABCC2
- MAOA
- NPY1R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- KDR
- LMNA
- LCK
- HTR6
- HTR2C
- HTR2A
- HTR1A
- HRH2
- HRH1
- HMGCR
- HDAC6
- NPY2R
- NR3C1
- FYN
- OPRD1
- USP2
- USP1
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ACM1
- CP1A2
- CP2D6
- GLI3
- NF2L2
- NR1I2
- RARA
Drug classes
- Anesthetics
- Anesthetics, Local
- Central Nervous System Agents
- Central Nervous System Depressants
- Peripheral Nervous System Agents
- Sensory System Agents
- topical anesthetic
ATC classes
- D04A · ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
- C05A · AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
Cross-references
Synonyms
- Curasore
- Dermal-Soothe
- EPIFOAM
- HYDROCORTISONE ACETATE 1% AND PRAMOXINE HYDROCHLORIDE 1%
- PRAMOSONE
- PROCTOFOAM HC
- pramocaine
- pramocaine hydrochloride
- pramoxine hydrochloride
- pramocain
- pramoxin
- pramoxine HCl
- Pramocaine
- Pramocaina
- Pramoxine hydrochloride
- Pramoxine HCl
- Pramocaine hydrochloride
- Prax Lotion
- Tronolane
- Tronothane hydrochloride
- ProctoFoam-NS
- Pramocaine (hydrochloride)
- UNII-88AYB867L5
- HSDB 7220
- EINECS 211-293-1
- NSC 25573
- Pramoxine hydrochloride [USP]
- MLS000028604
- Morpholine, 4-[3-(4-butoxyphenoxy)propyl]-, hydrochloride
- 88AYB867L5
- 4-(3-(p-Butoxyphenoxy)propyl)morpholine hydrochloride
- p-Butoxyphenyl gamma-morpholinopropyl ether hydrochloride
- gamma-Morpholinopropyl 4-n-butoxyphenyl ether hydrochloride
- SMR000058670
- 4-(3-(p-Butoxyphenoxy)propyl)morpholine
- Proxazocain
- pramocainum
Reported adverse events
- Hypertrichosis
- Perioral dermatitis
- Milia
- Acne
- Folliculitis
- Miliaria
- Skin atrophy
Look up PRAMOXINE in the interactive SynDRA portal →