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PROPARACAINE
SynDRA canonical compound SYN0004499 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SCN10A | SCN5A | SCN9A |
|---|
| Mechanism of action | sodium channel blocker |
|---|
| Indication | anesthetic |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SCN10A
- SCN1A
- SCN2A
- SCN3A
- SCN5A
- SCN9A
- SCN11A
- SCN4A
- SCN7A
- SCN8A
- MAOA
- SIGMAR1
Mechanisms of action (all sources)
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
- SCN10A BLOCKER
- sodium channel blocker
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- HRH3
- LCK
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- ACHE
- ADORA1
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH2
- HRH1
- HMGCR
- HDAC6
- GLS
- NR1I2
- NR3C1
- OPRD1
- PTGS1
- USP1
- TBXAS1
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- SAMHD1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AHR
- CFTR
- CP1A2
- CP2D6
- RAD52
- TP53
Drug classes
- Local Anesthetic
- Anesthetics
- Anesthetics, Local
- Central Nervous System Agents
- Central Nervous System Depressants
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
Cross-references
Synonyms
- ALCAINE
- Alcaine
- KAINAIR
- OPHTHAINE
- OPHTHETIC
- PARACAINE
- PROPARACAINE HYDROCHLORIDE
- proparacaine hydrochloride
- ophthaine
- proxymetacaine
- proparacaine HCl
- Proxymetacaine
- Proximetacaina
- Diocaine
- Kainair
- Ophthaine
- Ophthetic
- Paracaine
- Prossimetacaina
- Proximetacainum
- Proxymetacainum
- Prossimetacaina [DCIT]
- Proxymetacaine Hcl
- Ak-taine
- Alcaine (TN)
- Ocu-Caine
- Proximetacaina [INN-Spanish]
- Proxymetacaine (INN)
- Proxymetacaine [INN:BAN]
- Proxymetacainum [INN-Latin]
- Spectro-Caine
- Ak-Taine (TN)
- Beta-(Diethylamino)ethyl 4-n-propoxybenzoate
- 3-Amino-4-propoxybenzoic acid 2-(diethylamino)ethyl ester
- B4OB0JHI1X
- proxymethacaine
- RefChem:58606
- DTXCID60120637
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