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PRILOCAINE
SynDRA canonical compound SYN0004496 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SCN5A |
|---|
| Mechanism of action | Local anesthetic |
|---|
| Indication | anesthetic |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SCN5A
- SCN1A
- SCN2A
- SCN3A
- SCN10A
- SCN11A
- SCN4A
- SCN7A
- SCN8A
- SCN9A
Mechanisms of action (all sources)
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
- SCN10A BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRB2
- PGR
- DRD2
- ACHE
- LCK
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPT
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- HTR6
- KCNH2
- NPY1R
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HPGD
- HMGCR
- HDAC6
- MMP9
- NPY2R
- GAA
- NR1I2
- TBXAS1
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anesthetics
- Anesthetics, Local
- Central Nervous System Agents
- Central Nervous System Depressants
- Peripheral Nervous System Agents
- Sensory System Agents
- Amide Local Anesthetic
- Local anesthetic
ATC classes
- N01B · ANESTHETICS, LOCAL
Cross-references
Synonyms
- CITANEST
- CITANEST FORTE
- CITANEST FORTE DENTAL
- CITANEST PLAIN
- CITANEST PLAIN DENTAL
- Citanest
- EMLA
- LIDOCAINE AND PRILOCAINE
- ORAQIX
- PRILOCAINE HYDROCHLORIDE
- PRILOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE
- propitocaine hydrochloride
- propitocaine
- (+/-)-Prilocaine
- prilocaine hydrochloride
- propitocaine HCl
- prilocaine HCl
- Prilocaina
- Propitocaine
- ASTRA 1512
- ASTRA-1515
- NSC-40027
- Prilocaine component of emla
- Prilocaine component of fortacin
- Prilocaine component of oraqix
- Prilocainum
- Prilocaine [USAN]
- Prilocaine base
- Astra 1512
- Astra 1515
- L 67
- Citanest (TN)
- Prilocaina [INN-Spanish]
- Prilocainum [INN-Latin]
- Propitocaine (JAN)
- Prilocaine (USP/INN)
- O-Methyl-2-propylaminopropionanilide
- O-Methyl-alpha-propylaminopropionanilide
Reported adverse events
- Headache
- Nausea
- Arthralgia
- Arthropathy
- Dizziness
- Fatigue
- Myalgia
- Rhinitis
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