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PHENIRAMINE
SynDRA canonical compound SYN0004493 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HRH1 |
|---|
| Mechanism of action | Histamine receptor antagonist |
|---|
| Indication | allergic rhinitis | urticaria |
|---|
| Disease area | allergy |
|---|
All known targets
- HRH1
- HRH4
- SCN1A
- SCN2A
- SCN3A
Mechanisms of action (all sources)
- Histamine receptor antagonist
- HRH1 ANTAGONIST
- Histamine H1 receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SLC6A4
- ESR1
- ACHE
- RAB9A
- MAOA
- MBNL1
- NFE2L2
- OPRM1
- PDE3A
- PDE4A
- PGR
- POLI
- PTGS1
- RGS4
- KDR
- RORC
- SAMHD1
- SLC6A2
- SLC6A3
- SLCO1B1
- SLCO1B3
- SMAD3
- TBXA2R
- TSHR
- UGT1A4
- LMNA
- KDM4E
- ADORA3
- CYP2C19
- ADRA1A
- ADRA2A
- ALDH1A1
- AR
- ATAD5
- BAZ2B
- CBX1
- CHRM1
- CHRM2
- CYP1A2
- CYP2C9
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- CP1A2
- CP2D6
- NF2L2
- WEE1
Drug classes
- Anti-Allergic Agents
- Antipruritics
- Dermatologic Agents
- Histamine Agents
- Histamine Antagonists
- Histamine H1 Antagonists
- Neurotransmitter Agents
ATC classes
- D04A · ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
- R06A · ANTIHISTAMINES FOR SYSTEMIC USE
Cross-references
Synonyms
- NAPHAZOLINE HYDROCHLORIDE AND PHENIRAMINE MALEATE
- NAPHCON-A
- OPCON-A
- VISINE
- propheniramine
- prophenpyridamine
- pyriton
- tripoton
- pheniramine maleate
- Feniramina
- Propheniramine
- Prophenpyridamine
- Pyriton
- Tripoton
- NSC-47965
- Avil
- Feniramine
- Histapyridamine
- Metron
- Pheniraminum
- Trimeton
- Pheniramine Bimaleate
- Avil (TN)
- Feniramina [INN-Spanish]
- P-Aminosalicylsaures salz
- Pheniramine (INN)
- Pheniramine [INN:BAN]
- Pheniraminum [INN-Latin]
- PHENIRAMINE (SEE ALSO PHENIRAMINE MALEATE 132-20-7)
- Dimethyl(3-phenyl-3-(2-pyridyl)propyl)amine
- N,N-Dimethyl-3-phenyl-3-(2-pyridyl)propylamine
- 2-(3-Dimethylamino-1-phenylpropyl)pyridine
- 2-(alpha-(2-Dimethylaminoethyl)benzyl)pyridine
- 2-Pyridinepropanamine, N,N-dimethyl-gamma-phenyl-(9CI)
- 3-Phenyl-3-(2-pyridyl)-N,N-dimethylpropylamine
- 3-Phenyl-3-(2-pyridyl)-N,N-dimethylpropylanine
- NCI-C60695
- Prophenpyridamine; Pyriton
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