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TOLFENAMIC ACID
SynDRA canonical compound SYN0004396 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Mechanism of action | cyclooxygenase inhibitor | prostanoid receptor antagonist |
|---|
| Indication | migraine headache |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- AKR1C3
- AR
- MT-CO2
- PTGS1
- PTGS2
- TTR
Mechanisms of action (all sources)
- AKR1C3 INHIBITOR
- cyclooxygenase inhibitor
- prostanoid receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA1A
- ADORA1
- MC3R
- OPRM1
- OPRK1
- OPRD1
- NR3C1
- NR1I2
- NPY1R
- MLNR
- MAPT
- PDE4D
- MAOA
- LMNA
- KCNH2
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- PDE3A
- PGR
- HSPA5
- PLA2G1B
- USP2
- USP1
- UGT2B7
- UGT2B15
- UGT1A9
- UGT1A7
- UGT1A1
- TOP1
- TDP1
- TBXA2R
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SAMHD1
- HTR1A
- HRH3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ACM1
- S12A5
- RPGF4
- RGS12
- RAPGEF4
- PRGR
- PPARG
- PPARD
- PHGDH
- PA21B
- NF2L2
- GPR151
- GNAI1
- GCR
- FABP2
- CP3A7
- CP2C9
- CP1A2
- ALR
- AK1C3
- TP53
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Calcium Channel Blockers
- Calcium-Regulating Hormones and Agents
- Cardiovascular Agents
- Central Nervous System Agents
- Hormone Antagonists
- Membrane Transport Modulators
- Neurotransmitter Agents
ATC classes
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Cross-references
Synonyms
- tolfedine
- tolfine
- Acide tolfenamique
- Acido tolfenamico
- N-(3-chloro-o-tolyl)anthranilic
- NSC-757873
- Clotam
- Clotam rapid
- tolfenamic-acid
- 2-[(3-Chloro-2-methylphenyl)amino]benzoic Acid
- 2-((3-Chloro-2-methylphenyl)amino)benzoic acid
- N-(3-Chloro-2-methylphenyl)anthranilic acid
- Acidum tolfenamicum
- N-(3-Chloro-o-tolyl)anthranilic acid
- N-(2-Methyl-3-chlorophenyl)anthranilic acid
- N-(3-Chloro-o-tolyl)-anthranilic acid
- NSC 757873
- 3G943U18KM
- DTXCID9025409
- CHEBI:32243
- 2-([3-Chloro-2-methylphenyl]amino)benzoic acid
- RefChem:933170
- M01AG02
- GEA 6414
- 2-(3-Chloro-2-methylanilino)benzoic acid
- Tolfedine
- Benzoic acid, 2-[(3-chloro-2-methylphenyl)amino]-
- MFCD00133865
- N-(3-Chloro-ortho-tolyl) anthranilic acid
- Anthranilic acid, N-(3-chloro-o-tolyl)-
- NCGC00016705-05
- Bifenac
- CAS-13710-19-5
- Benzoic acid, 2-((3-chloro-2-methylphenyl)amino)-
- Tolfine
- SR-01000000102
- Tolfenamic
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