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CYCLOHEXIMIDE
SynDRA canonical compound SYN0004378 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | RPL3 |
|---|
| Mechanism of action | Protein synthesis inhibitor |
|---|
All known targets
- RPL3
- FAU
- RPL7
- RPS2
- RPS19
- RPS18
- RPS17
- RPS16
- RPS15A
- RPS15
- RPS14
- RPS13
Mechanisms of action (all sources)
- Protein synthesis inhibitor
- RPSA INHIBITOR
- RPS27 INHIBITOR
- RPS6 INHIBITOR
- RPS2 INHIBITOR
- RPS3 INHIBITOR
- RPS3A INHIBITOR
- RPS4X INHIBITOR
- RPS4Y1 INHIBITOR
- RPS5 INHIBITOR
- RPS7 INHIBITOR
- RPS8 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HIF1A
- FKBP1A
- DRD2
- EIF4A1
- ESR1
- SLC2A1
- NPY1R
- NPC1
- NFKB1
- NPY2R
- MAPK3
- MMP9
- NR1H4
- MMP1
- MC5R
- NR2F2
- MC4R
- NR3C1
- MC3R
- NFE2L2
- MAPK1
- MAPK14
- OPRK1
- MAOB
- MAOA
- LCK
- KCNH2
- IDH1
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HSP90AA1
- HSF1
- HRH2
- HRH1
- OPRD1
- ACHE
- HMGCR
- TACR2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AHR
- NSD2
- MDR1
- MITF
- NCOA1
- NCOA2
- NCOA3
- NOD2
- NR5A2
- PRGR
- MDM2
- PRIO
- RARA
- RIPK2
- SMAD2
- STK33
- SYK
- TFE3
- MDM4
- KSYK
- ANDR
- EPAS1
- BARD1
- BRCA1
- CFTR
- COT2
- CP19A
- CREB1
- CSTA
- ESRRA
- IL1B
- GCR
- GLI3
- HLAB
- HS90A
- IDHC
- IFNB1
- IFNG
- YAP1
Drug classes
- Antifungal Agents
- Protein Synthesis Inhibitors
Cross-references
Synonyms
- Cicloheximide
- Cicloheximida
- GNF-Pf-5118
- NSC-171
- NSC-185
- TCMDC-125838
- U-4527
- naramycin A
- NSC 185
- FT 3422-2
- NM-MCD 80
- ACTIDIONE
- NARAMYCIN A
- Kaken
- Actidion
- Actidone
- Hizarocin
- Naramycin
- Neocycloheximide
- Acti-Aid
- Cycloheximid
- Actispray
- Actidione PM
- Cicloheximidum
- Zykloheximid
- Cycloheximide [USAN]
- C15H23NO4
- U 4527
- Acti-dione BR
- 4-[(2R)-2-[(1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione
- 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione
- CBC 500046
- NSC185
- Cicloheximide [INN]
- Acti-Dione
- Actidione TGF
- 3-((R)-2-((1S,3S,5S)-3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)glutarimide
- Aktidion
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