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ERGONOVINE
SynDRA canonical compound SYN0004354 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ADRA1A | HTR1E |
|---|
| Mechanism of action | adrenergic receptor agonist | serotonin receptor agonist |
|---|
| Indication | postpartum hemorrhage (PPH) |
|---|
| Disease area | hematology |
|---|
All known targets
- HTR1E
- DRD2
- ADRA1A
- Htr1b
- Htr1a
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1D
- ADRA1B
- HTR1A
Mechanisms of action (all sources)
- adrenergic receptor agonist
- serotonin receptor agonist
- adrenergic receptor agonist, serotonin receptor agonist
- DRD2 AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB1
- MAPK1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPT
- MAPK3
- MAPK14
- MAOA
- ACHE
- LMNA
- LCK
- KMT2A
- KDM4E
- KCNH2
- KAT2A
- HSD17B10
- HRH2
- HRH1
- HPGD
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- VDR
- TDP1
- TBXAS1
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A3
- SLC6A2
- SIGMAR1
- RGS4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Oxytocics
- Reproductive Control Agents
ATC classes
Cross-references
Synonyms
- ergometrine
- ergonovine maleate
- ergometrine maleate
- ergometrin
- ergostetrine
- ergotocine
- ergobasine
- Ergometrine
- Ergometrina
- Ergobasine
- Ergostetrine
- Ergotocine
- Basergin
- Ergobasin
- Ergoklinine
- Ergometrin
- Ergometrinum
- Ergotrate
- Margonovine
- Neofemergen
- Secacornin
- Secometrin
- Ergotrate Maleate
- Lysergic acid propanolamide
- Ergometrina [INN-Spanish]
- Ergometrine (INN)
- Ergometrine [INN:BAN]
- Ergometrinum[INN-Latin]
- D-Lysergic acid 1-hydroxymethylethylamide
- D-Lysergic acid-L-propanolamide
- L-Lysergic-L(beta-hydroxyisopropylamide)
- N-(1-(Hydroxymethyl)ethyl)-D-lysergamide
- N-(alpha-(Hydroxymethyl)ethyl)-D-lysergamide
- N-(2-Hydroxy-1-methylethyl)-D(+)-lysergamide
- N-[(2S)-1-hydroxypropan-2-yl]-6-methyl-9,10-didehydroergoline-8beta-carboxamide
- [8beta(S)]-9,10-didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8-carboxamide
- 9,10-Didehydro-N-(2-hydroxy-1-methylethyl)-6-methylergoline-8beta(S)-carboxamide
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