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ZOLMITRIPTAN
SynDRA canonical compound SYN0004352 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HTR1F |
|---|
| Mechanism of action | Serotonin receptor agonist |
|---|
| Indication | migraine headache |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- HTR1B
- HTR1D
- HTR1A
- HTR1F
- HTR1E
- Adra2a
- Adra2b
- Adra2c
- Drd1
- Drd2
Mechanisms of action (all sources)
- Serotonin receptor agonist
- HTR1B AGONIST
- Serotonin 1b (5-HT1b) receptor agonist
- HTR1D AGONIST
- Serotonin 1d (5-HT1d) receptor agonist
- HTR1B MODULATOR
- HTR1D MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB1
- ADORA1
- HTR3A
- HTR4
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- POU2F1
- POU2F2
- PPARG
- PTGS2
- SLC22A3
- SLC29A1
- SLC47A1
- SLC47A2
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- HTR2C
- HTR2B
- HTR2A
- CHRM1
- ADORA2A
- ADORA3
- ADRA1A
- ADRB1
- ADRB2
- AGTR1
- APEX1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT1A
- 5HT1E
- 5HT1F
- 5HT2A
- RAPGEF4
- RPGF4
Drug classes
- Neurotransmitter Agents
- Serotonin 5-HT1 Receptor Agonists
- Serotonin Agents
- Serotonin Receptor Agonists
- Serotonin 1b Receptor Agonists
- Serotonin 1d Receptor Agonists
- Serotonin-1b and Serotonin-1d Receptor Agonist
ATC classes
- N02C · ANTIMIGRAINE PREPARATIONS
Cross-references
Synonyms
- ZOMIG
- ZOMIG-ZMT
- Zomig
- zipton
- zominat
- zomigoro
- 311C90
- Cvt-427
- 311-C-90
- NSC-760383
- Zomig-zmt
- AscoTop
- Flezol
- Zolmitriptane
- Zolmitriptanum
- Zomigon
- Zolmitriptan RapidFilm
- Zolmitriptan [USAN]
- Zomig Nasal Spray
- Zomig-ZMT
- AscoTop (TN)
- BW-311C90
- KS-5072
- Zomig (TN)
- Zomigon (TN)
- Zomigoro (TN)
- Zomig, Zomigon, AscoTopand, Zomigoro, Zolmitriptan
- Zomigoro
- Zomig ZMT
- C16H21N3O2
- NSC 760383
- 2FS66TH3YW
- CHEMBL1185
- CHEBI:10124
- AscoTopand
- zolmitriptane
- zolmitriptanum
Reported adverse events
- Asthenia
- Nausea
- Somnolence
- Dizziness
- Headache
- Pain
- Hypersensitivity
- Serotonin syndrome
- Vasospasm
- Dysphagia
- Arrhythmia
- Dry mouth
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