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TRICIRIBINE
SynDRA canonical compound SYN0004308 — structure-anchored drug synonym record
| Clinical phase | Phase 1/Phase 2 |
|---|
| Primary target(s) | AKT2 |
|---|
| Mechanism of action | Akt inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- AKT1 INHIBITOR
- HIV RT INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SYK
- HDAC6
- ABL1
- PLK2
- PDGFRA
- PDGFRB
- PDPK1
- PHKG2
- PIM1
- PIM2
- PIM3
- PKN2
- PLK1
- PLK3
- PAK6
- PRKACA
- PRKCA
- PRKCB
- PRKCD
- PRKCE
- PRKCG
- PRKCH
- PRKCI
- PRKCQ
- PRKCZ
- PRKD1
- PASK
- PAK5
- PRKG1
- PAK4
- MAPKAPK5
- MARK1
- MARK2
- MELK
- MERTK
- MET
- MINK1
- MKNK2
- MST1R
- MTOR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AHR
- ANDR
- PNMT
- NTMT1
- NTM1A
- NR1I3
- NR1I2
- NNMT
- NF2L2
- KSYK
- HNMT
- GNMT
- GLI3
- GAMT
- ESR1
- DRD3
- CP3A4
- CP19A
- COMT
- RARA
Cross-references
Synonyms
- NSC154020
- Akt Inhibitor V, Triciribine
- MLS002702033
- Akt/PKB Signaling Inhibitor-2
- NSC-154020
- TCN
- Akt inhibitor V
- AC1Q7CGY
- AC1L6DVE
- tricyclic nucleoside (TCN)
- SCHEMBL61269
- GTPL5920
- CHEMBL1892348
- CHEBI:91697
- HMS3268N05
- HMS3654C06
- HMS3229A09
- HSCI1_000386
- CCG-206732
- 5-methyl-1-pentofuranosyl-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylen-3-amine
- SMR001565606
- SC-89664
- NCI60_001091
- Akt/protein kinase B signaling inhibitor-2
- BRD-A42649439-001-01-0
- BRD-A42649439-001-02-8
- 1,5,6,8-Pentaazaacennaphthylen-3-amine, 1,5-dih
- API-2
- Tricyclic nucleoside
- Pentaazacentopthylene
- Triciribine [INN]
- Tricirbine
- BRN 1171593
- 1,5-Dihydro-5-methyl-1-beta-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine
- CHEBI:65310
- 2421HMY9N6
- 1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-beta-D-ribofuranosyl-
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