← SynDRA
DESLORATADINE
SynDRA canonical compound SYN0004255 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HRH1 |
|---|
| Mechanism of action | Histamine receptor antagonist |
|---|
| Indication | allergic rhinitis | urticaria |
|---|
| Disease area | allergy |
|---|
All known targets
- HRH1
- HRH2
- SLC6A3
- SLC6A2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HRH4
- ABCB1
- ADRA2B
- DRD3
Mechanisms of action (all sources)
- Histamine receptor antagonist
- HRH1 ANTAGONIST
- Histamine H1 receptor antagonist
- SLC6A15 INHIBITOR
- TRPV2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR2
- DRD4
- DRD1
- DRD2
- KCNH2
- ADRA1A
- HCAR2
- LMNA
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- HDAC6
- KDR
- NPY1R
- GHSR
- GIPR
- HTR3A
- HTR1A
- HRH3
- HMGCR
- MMP9
- NPY2R
- FYN
- PTGS1
- VDR
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC29A1
- SIGMAR1
- SAMHD1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- GPR151
- RGS4
- RARA
- PPARD
- NR1I2
- NR1H4
- MDM4
- MDM2
- M4K2
- GLI3
- ACM1
- CREB1
- CP3A7
- CP3A4
- CP2D6
- CASP7
- CASP3
- ATXN2
- ANDR
- TSHR
Drug classes
- Histamine H1 Receptor Antagonists
- Histamine-1 Receptor Antagonist
- Cholinergic Agents
- Cholinergic Antagonists
- Histamine Agents
- Histamine Antagonists
- Histamine H1 Antagonists
- Histamine H1 Antagonists, Non-Sedating
- Neurotransmitter Agents
- Anti-Allergic Agents
- Antipruritics
- Dermatologic Agents
ATC classes
- R06A · ANTIHISTAMINES FOR SYSTEMIC USE
Cross-references
Synonyms
- CLARINEX
- CLARINEX D 24 HOUR
- CLARINEX-D 12 HOUR
- Clarinex
- DESLORATADINE AND PSEUDOEPHEDRINE SULFATE 24 HOUR
- SCH 34117
- azomyr
- delopedil
- descarboethoxyloratadine
- descarboethoxyloratidine
- neoclarityn
- Desloratadina
- Allex
- Azomyr
- Dasselta
- Denosin
- Descarboethoxyloratadine
- Desloratadine actavis
- Desloratadine teva
- Opulis
- NSC-759824
- SCH-34117
- Aerius
- Desloratadine actavis (authorized: rhinitis, urticaria)
- Desloratadine component of clarinex-d
- Desloratadine ratiopharm
- Desloratadine ratiopharm (authorized: rhinitis, urticaria)
- Desloratadine teva (authorized: rhinitis, urticaria)
- Midetorin
- Neoclarityn
- Loratadine related compound a
- Loratadine related compound a rs
- Claramax
- Desalex
- Descarboethoxyoratidine
- Desloratidine
- Clarinex RediTabs
Reported adverse events
- Fatigue
- Myalgia
- Hypersensitivity
- Somnolence
- Pharyngitis
- Infestation
Look up DESLORATADINE in the interactive SynDRA portal →