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AMINOSALICYLIC ACID
SynDRA canonical compound SYN0004231 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
| Indication | inflammatory bowel disease | ulcerative colitis |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- PTGS1
- PTGS2
- ALOX5
- CHUK
- DHFR
- PLA2G2E
- PTPN1
- folK
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- PTGS1 MODULATOR
- PTGS2 MODULATOR
- DHFR MODULATOR
- PTGS1 INHIBITOR
- PTGS2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ESR2
- ACHE
- MAOA
- MMP8
- MMP3
- MMP2
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MBNL1
- MAPT
- MAPK3
- MAPK14
- MAPK1
- LCK
- GNAS
- KDM4E
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- MMP9
- NPY1R
- NPY2R
- NR1I2
- UGT1A9
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP3A4
- GNAI1
- MITF
- RGS12
- SIRT5
Drug classes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antitubercular Agents
ATC classes
- J04A · DRUGS FOR TREATMENT OF TUBERCULOSIS
Cross-references
Synonyms
- NEOPASALATE
- P.A.S. SODIUM
- PARASAL
- PARASAL SODIUM
- PASER
- PASKALIUM
- POTASSIUM AMINOSALICYLATE
- REZIPAS
- SODIUM AMINOSALICYLATE
- SODIUM P.A.S.
- TEEBACIN
- aminosalicylic acid resin complex
- potassium aminosalicylate
- p-aminosalicylic acid
- 4-Aminosalicylic acid
- 4-Carboxy-3-hydroxyaniline
- apacil
- calcium aminosalicylate
- sodium aminosalicylate
- para-aminosalicylic acid
- aminosalicylate potassium
- aminosalicylate sodium
- teebacin
- 4-aminosalicylic acid
- Para-aminosalicylic acid
- Aminosalicylic acid resin complex
- P-aminosalicylic acid
- Aminosalicylate
- Benzoic acid, 4-amino-2-hydroxy-
- Pas
- NSC-2083
- Aminosalicylic acid component of neopasalate
- Granupas
- Granupas (previously para-aminosalicylic acid lucane)
- Parasal
- Paser
- Rezipas
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