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RAMIPRIL
SynDRA canonical compound SYN0004220 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ACE |
|---|
| Mechanism of action | Angiotensin converting enzyme inhibitor |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
Mechanisms of action (all sources)
- ACE inhibitor
- SLC33A1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- HTR6
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KCNH2
- IDH1
- HTR3A
- FYN
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- HCAR2
- GIPR
- GHSR
- MMP9
- NPY1R
- NPY2R
- NR3C1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Angiotensin-converting Enzyme Inhibitors
- Angiotensin Converting Enzyme Inhibitor
- Antihypertensive Agents
- Cardiovascular Agents
- Enzyme Inhibitors
- Protease Inhibitors
ATC classes
- C09A · ACE INHIBITORS, PLAIN
- ACE INHIBITORS, COMBINATIONS
- LIPID MODIFYING AGENTS, COMBINATIONS
Cross-references
Synonyms
- ALTACE
- Altace
- VOSTALLY
- Vostally
- HOE498
- HOE-498
- Cardace
- Corpril
- Delix
- Ecator
- Hopace
- Pramace
- Ramace
- Ramipres
- Triatec
- Unipril
- Vesdil
- C09AA05
- NSC-758933
- Lopace
- Ramipril component of polycap
- Ranace
- Tritace
- Acovil
- Carasel
- Hypren
- Hytren
- Lostapres
- Naprix
- Quark
- Ramiprilum
- Zabien
- Almirall Brand of Ramipril
- Astra Brand of Ramipril
- AstraZeneca Brand of Ramipril
- Aventis Brand of Ramipril
- Aventis Pharma Brand of Ramipril
Reported adverse events
- Angioedema
- Hypotension
- Arthralgia
- Vertigo
- Stevens-Johnson syndrome
- Anaphylactoid reaction
- Anxiety
- Hepatic failure
- Pancytopenia
- Cough
- Dizziness
- Nausea
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