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ATAZANAVIR
SynDRA canonical compound SYN0004202 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | HIV protease inhibitor |
|---|
| Indication | human immunodeficiency virus (HIV-1) |
|---|
| Disease area | infectious disease |
|---|
All known targets
- ABCB1
- ABCG2
- CYP1A2
- CYP2C9
- CYP3A4
- HIV PR
- HIV-1 protease
- UGT1A1
- gag-pol
- pol
- protease
Mechanisms of action (all sources)
- protease inhibitor
- HIV PR MODULATOR
- pol INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- SLCO2B1
- SLCO1B3
- SLCO1B1
- MLNR
- OPRK1
- KCNH2
- MC4R
- MC3R
- MAOA
- HTR2C
- HTR3A
- NR1I2
- HTR2B
- HTR2A
- HTR1A
- NPY1R
- OPRD1
- NR3C1
- ADORA1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- HRH3
- HRH2
- HRH1
- BDKRB2
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP2C9
- CP2CJ
- CP3A4
- CP3A7
- PLCB3
- PLCG1
Drug classes
- HIV Protease Inhibitors
- Anti-HIV Agents
- Anti-Infective Agents
- Anti-Retroviral Agents
- Antiviral Agents
- Enzyme Inhibitors
- Protease Inhibitors
- Viral Protease Inhibitors
- Protease Inhibitor
- Cytochrome P450 3A4 Inhibitors
- Cytochrome P450 2C8 Inhibitors
- Cytochrome P450 3A Inhibitors
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- ATAZANAVIR SULFATE
- EVOTAZ
- Evotaz
- REYATAZ
- Reyataz
- BMS-232632
- reyataz
- atazanavir sulphate
- atazanavir sulfate
- CGP-73547
- Latazanavir
- Zrivada
- BMS 232632
- Atazanavir [INN:BAN]
- Atazanavir Base
- UNII-QZU4H47A3S
- HSDB 7339
- Reyataz (TN)
- ATV
- QZU4H47A3S
- CHEMBL1163
- CHEBI:37924
- NCGC00182552-01
- AK174307
- DSSTox_CID_28617
- DSSTox_RID_82887
- DSSTox_GSID_48691
- DR7
- atazanavirum
- ATZ
- Atazanavir (INN)
- Reyataz, BMS-232632, Atazanavir
- Reyataz(TM) (*1:1 sulfate*)
- DTXCID5028617
- RefChem:54330
- J05AE08
- ATAZANAVIR [INN]
- MFCD08435966
Reported adverse events
- Rash
- Jaundice
- Nausea
- Abdominal pain
- Dizziness
- Headache
- Insomnia
- Myalgia
- Vomiting
- Lipase
- Depression
- Hepatitis
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