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NORETHINDRONE
SynDRA canonical compound SYN0004198 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PGR |
|---|
| Mechanism of action | progesterone receptor agonist |
|---|
| Indication | endometriosis |
|---|
| Disease area | obstetrics/gynecology |
|---|
All known targets
- PGR
- AR
- Ar
- ESR1
- Esr1
- Esr2
- NR3C1
- SHBG
- SLC6A4
- CYP2C19
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- MAOA
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- ABCB1
- NR3C2
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- LCK
- OPRD1
- ABCB11
- SIGMAR1
- UGT1A1
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A3
- SLC6A2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP2C9
- CP2CJ
- CP3A4
- CP3A7
- ESRRA
- GCR
- GLI3
- GPR32
- MDR1
- NF2L2
- NSD2
- RARA
Drug classes
- Contraceptive Agents
- Contraceptive Agents, Female
- Contraceptive Agents, Hormonal
- Contraceptives, Oral, Hormonal
- Contraceptives, Oral, Synthetic
- Reproductive Control Agents
- Progestin
- Progestogen hormone
- contraceptive agent
ATC classes
- G03D · PROGESTOGENS
- G03A · HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
- PROGESTOGENS AND ESTROGENS IN COMBINATION
- HYPOTHALAMIC HORMONES
Cross-references
Synonyms
- ALYACEN 1/35
- ALYACEN 7/7/7
- ARANELLE
- Aygestin
- BALZIVA-21
- BALZIVA-28
- BREVICON 21-DAY
- BREVICON 28-DAY
- BRIELLYN
- CAMILA
- CYCLAFEM 0.5/35
- CYCLAFEM 1/35
- norethisterone
- norethisteron
- norethynodrone
- Norethisterone
- Noretisterona
- Activella
- Anovule
- Calluna vulgaris
- Calluna vulgaris whole
- Combipatch
- Femhrt
- Gestest
- Heather whole
- Norethisteron
- Norethisteronum
- Triella
- NSC-9564
- SC-4640
- Camila
- Errin
- Heather
- Incassia
- Jencycla
- Menzol
- Micronor
- Micronor hrt
Reported adverse events
- Cancer
- Dementia
- DVT
- TIA
- Breast cancer
- Cardiovascular disorder
- Nausea
- Headache
- Vomiting
- Migraine
- Erythema nodosum
- Thrombophlebitis
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