← SynDRA

PINACIDIL ANHYDROUS

SynDRA canonical compound SYN0004192 — structure-anchored drug synonym record

All known targets

• ABCC9
• KCNJ11
• ABCC8
• KCNJ8
• KCNMA1

Mechanisms of action (all sources)

• ATP channel activator
• Potassium channel activator
• KCNJ11 OPENER
• Sulfonylurea receptor 2, Kir6.2 opener
• ABCC9 OPENER

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ACHE
• ADORA3
• LMNA
• MAOA
• MPHOSPH8
• NFE2L2
• NPSR1
• OPRM1
• PDE3A
• PDE4A
• PGR
• PMP22
• PTGS1
• RAPGEF4
• SAMHD1
• SLC6A2
• SLC6A3
• SLC6A4
• SLCO1B1
• SLCO1B3
• TBXA2R
• KDR
• KCNH2
• HTR2B
• CYP3A4
• ADRA1A
• ADRA2A
• ALDH1A1
• AR
• BLM
• CBX1
• CHRM1
• CHRM2
• DRD1
• HTR1A
• DRD3
• EHMT2
• ESR1
• F2
• GLA

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• CP2C9
• CP2CJ
• CP2D6
• CP3A4
• MDR1

Drug classes

• Antihypertensive Agents
• Cardiovascular Agents
• Membrane Transport Modulators
• Vasodilator Agents

ATC classes

• C02D · ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON
• ANTIHYPERTENSIVES AND DIURETICS IN COMBINATION

Cross-references

• PubChem CID: 4826
• ChEMBL: CHEMBL1159
• DrugBank: DB06762
• ChEBI: CHEBI:34923
• KEGG: D05482
• RxNorm: 33717
• Wikipedia: Pinacidil
• TTD: D02KMO
• LINCS BRD: BRD-A22897758

Synonyms

• PINDAC
• pinacidil
• (R,S)-Pinacidil
• pinacidil monohydrate
• pindac
• (+/-)-Pinacidil
• pinacidil hydrate
• (r,s)-pinacidil
• P-1134
• S-1230
• Pinacidil
• Pinacidilum
• P 1134
• P-154
• Pinacidil (anhydrous)
• Pinacidilum [INN-Latin]
• (+-)-Pinacidil
• Pinacidil [INN]
• MLS000069377
• SMR000058360
• P-1134;S-1230
• SR-01000075340
• SR-05000001757
• NCGC00025188-04
• EINECS 262-294-9
• UNII-BB4UGO5K0D
• Prestwick_396
• Pinacidil (Standard)
• Spectrum_000387
• SpecPlus_000759
• PINACIDIL [MI]
• Opera_ID_1844
• Prestwick0_000246
• Prestwick1_000246
• Prestwick2_000246
• Prestwick3_000246
• Spectrum2_001739
• Spectrum5_001372
• PINACIDIL [WHO-DD]