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NYLIDRIN
SynDRA canonical compound SYN0004185 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ADRB2 |
|---|
| Mechanism of action | Adrenergic receptor agonist |
|---|
| Indication | Raynaud's disease |
|---|
| Disease area | rheumatology |
|---|
All known targets
- ADRB2
- ADRA1A
- ADRA1B
- ADRA1D
Mechanisms of action (all sources)
- Adrenergic receptor agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR2A
- KCNH2
- OPRK1
- OPRM1
- HTR2B
- NPY2R
- NPY1R
- DRD2
- SLC6A3
- DRD3
- HTR1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- HTR6
- NR3C1
- MPHOSPH8
- HTR5A
- MC4R
- MC3R
- MAOA
- LMNA
- HTR2C
- HTR3A
- HTR7
- MLNR
- ADORA1
- NTSR1
- SLC6A2
- TDP1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC29A1
- OPRD1
- SAMHD1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- CP2CJ
- CP2D6
- CP3A7
- JUN
Drug classes
- Adrenergic Agents
- Adrenergic Agonists
- Adrenergic beta-Agonists
- Cardiovascular Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
- Reproductive Control Agents
- Sympathomimetics
- Tocolytic Agents
- Vasodilator Agents
ATC classes
- G02C · OTHER GYNECOLOGICALS
- C04A · PERIPHERAL VASODILATORS
Cross-references
Synonyms
- buphenine
- nylidrin hydrochloride
- buphenin
- nilidrine
- nylidrin HCl
- Buphenine
- Bufenina
- Buphenin
- Nilidrine
- Suprifen-psb
- Phenyl-sec-butyl norsuprifen
- 4-[1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl]phenol
- Benzenemethanol, 4-hydroxy-alpha-(1-((1-methyl-3-phenylpropyl)amino)ethyl)-
- 4-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]propyl}phenol
- p-Hydroxy-N-(1-methyl-3-phenylpropyl)norephedrine
- 695DKH33EI
- 1-(p-Hydroxyphenyl)-2-(1'-methyl-3'-phenylpropylamino)-1-propanol
- Buphenine (INN)
- NCGC00015716-05
- Nylidrinum
- BUPHENINE [INN]
- 4-(1-Hydroxy-2-((4-phenylbutan-2-yl)amino)propyl)phenol
- Bupheninum
- Bufenina [INN-Spanish]
- Bupheninum [INN-Latin]
- Benzenemethanol, 4-hydroxy-.alpha.-[1-[(1-methyl-3-phenylpropyl)amino]ethyl]-
- CAS-447-41-6
- HSDB 3137
- Buphenine [INN:BAN]
- SKF 1700-A
- EINECS 207-182-2
- CS 6712
- UNII-695DKH33EI
- SR-01000002981
- BENZENEMETHANOL, 4-HYDROXY-.ALPHA.-(1-((1-METHYL-3-PHENYLPROPYL)AMINO)ETHYL)-
- Spectrum_001043
- NYLIDRIN [HSDB]
- NYLIDRIN [MI]
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