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ZM-241385
SynDRA canonical compound SYN0004166 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | ADORA2B |
|---|
| Mechanism of action | Adenosine receptor antagonist |
|---|
All known targets
- ADORA1
- ADORA2A
- ADORA2B
- ADORA3
Mechanisms of action (all sources)
- Adenosine receptor antagonist
- ADORA1 ANTAGONIST
- ADORA2A ANTAGONIST
- ADORA2B ANTAGONIST
- ADORA3 ANTAGONIST
- ADORA1 INHIBITOR
- ADORA2B INHIBITOR
- ADORA2A INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TMEM97
- HTR2B
- ADGRF1
- OPRD1
- HTR1B
- HTR1D
- HTR2A
- HTR2C
- HTR3A
- HTR7
- MAPK1
- MPG
- MUTYH
- NEIL1
- NEIL2
- OGG1
- OPRK1
- HSD17B10
- OPRM1
- RGS4
- S1PR1
- SIGMAR1
- SLC6A2
- SLC6A3
- SLC6A4
- SMN1
- SMUG1
- TDG
- TDP1
- TSPO
- HTR1A
- HDAC6
- ADRA1A
- CYP1A2
- ADRA1B
- ADRA1D
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AA1R
- AA2AR
- AA2BR
- CP1A2
- CP3A4
- IFNG
- MAPT
- TMIG3
Cross-references
Synonyms
- ZM 241385
- ZM241385
- CHEMBL113142
- 4-(2-(7-Amino-2-(2-furyl)(1,2,4)triazolo(2,3-a)(1,3,5)triazin-5-ylamino)ethyl)phenol
- 4-(2-[7-Amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol
- 4-(2-(7-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)ethyl)phenol
- 4-{2-[(7-Amino-2-Furan-2-Yl[1,2,4]triazolo[1,5-A][1,3,5]triazin-5-Yl)amino]ethyl}phenol
- 4-[2-[[7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl]amino]ethyl]phenol
- RefChem:511345
- 5NIC36BO71
- ZM-241,385
- C16H15N7O2
- [3H]-ZM241385
- 3eml
- 3pwh
- PWTBZOIUWZOPFT-UHFFFAOYSA-N
- MFCD00908394
- Tocris-1036
- UNII-5NIC36BO71
- GTPL405
- SCHEMBL194966
- orb1300136
- BDBM21190
- CHEBI:92361
- EX-A944
- GLXC-02813
- HMS3267A14
- HMS3412A19
- HMS3676A19
- HMS3742O05
- HMS3886P04
- HB2096
- PDSP1_001201
- PDSP2_001185
- s8105
- AKOS024456344
- CCG-267879
- CS-5528
- NCGC00024955-01
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