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CORTICOSTERONE
SynDRA canonical compound SYN0004125 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | HSD11B1 | NCOA1 | NR3C2 |
|---|
| Mechanism of action | mineralocorticoid receptor agonist |
|---|
All known targets
- HSD11B1
- NR3C2
- NCOA1
- NR3C1
Mechanisms of action (all sources)
- mineralocorticoid receptor agonist
- NR3C1 AGONIST
- HSD11B1 INHIBITOR
- NR3C2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SERPINA6
- SHBG
- SLC22A1
- SLC22A3
- ABCB1
- RORC
- SIGMAR1
- SLC22A11
- SLC22A2
- SLC22A5
- SLC22A8
- SMN1
- TDP1
- THPO
- THRB
- UGT1A1
- UGT1A4
- SAMHD1
- PGR
- AR
- NR1H4
- CBX1
- CYP3A4
- EBP
- EHMT2
- GALC
- GMNN
- HDAC6
- HIF1A
- HSD17B10
- HSD17B7
- IDH1
- MAPK1
- MTOR
- NFE2L2
- NFKB1
- UGT2B15
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP1A2
- CP2C9
- CP2CJ
- CREB1
- ESRRA
- GCR
- GLI3
- IF4H
- NF2L2
- NR1I2
- PRGR
- TSHR
Drug classes
Cross-references
Synonyms
- 11-b,21-dihydroxypregn-3,20-dione
- 17-deoxycortisol
- Kendall's compound b
- Preg-4-ene-3,20-dione,11-b,21-dihydroxy-
- Reichstein's substance h
- NSC-9705
- (11-BETA)-11,21-DIHYDROXY-PREGN-4-ENE-3,20-DIONE
- 17-Deoxycortisol
- Reichstein's substance H
- Kendall's compound B
- Corticosteron
- 11beta,21-Dihydroxyprogesterone
- Compound B
- Reichstein's B
- 11-Hydroxycorticoaldosterone
- (11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione
- 11beta,21-Dihydroxy-4-pregnene-3,20-dione
- 4-Pregnene-11beta,21-diol-3,20-dione
- 11,21-Dihydroxyprogesterone
- 11Beta,21-dihydroxypregn-4-ene-3,20-dione
- 11,12-Dihydroxyprogesterone
- UNII-W980KJ009P
- CCRIS 6753
- 11-beta,21-Dihydroxypregn-3,20-dione
- CHEBI:16827
- NSC9705
- BRD-K73589401
- NSC 9705
- W980KJ009P
- DTXCID702474
- RefChem:579253
- 4-Pregnene-11-beta,21-diol-3,20-dione
- Corticosterone (Standard)
- MFCD00037715
- Pregn-4-ene-3,20-dione, 11beta,21-dihydroxy-
- Pregn-4-ene-3,20-dione, 11-beta,21-dihydroxy-
- (11-beta)-11,21-Dihydroxypregn-4-ene-3,20-dione
- MLS000028536
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