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PRAVASTATIN
SynDRA canonical compound SYN0004074 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HMGCR |
|---|
| Mechanism of action | HMGCR inhibitor |
|---|
| Indication | hypercholesterolemia | hyperlipidemia | myocardial infarction |
|---|
| Disease area | cardiology | endocrinology |
|---|
All known targets
- HMGCR
- Hmgcr
- SLCO1B1
- Slc22a6
Mechanisms of action (all sources)
- HMGCR INHIBITOR
- HMG-CoA reductase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SLCO2B1
- DRD2
- ABCB1
- MAOA
- NR1I2
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- LCK
- OPRD1
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HDAC6
- NR3C1
- OPRK1
- FYN
- SLC22A1
- TDP1
- TBXAS1
- TACR2
- TACR1
- SQLE
- SLCO1B3
- SLCO1A2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- HMG-CoA Reductase Inhibitor
- Anticholesteremic Agents
- Antimetabolites
- Enzyme Inhibitors
- Hypolipidemic Agents
- Lipid Regulating Agents
ATC classes
- C10A · LIPID MODIFYING AGENTS, PLAIN
- LIPID MODIFYING AGENTS, COMBINATIONS
Cross-references
Synonyms
- PRAVACHOL
- PRAVASTATIN SODIUM
- PRAVIGARD PAC (COPACKAGED)
- Pravachol
- eptastatin
- mevalothin
- pravastatin acid
- pravastatin sodium
- pravachol
- Pravastatine
- Pravastatina
- Pravator
- C10AA03
- Eptastatin
- Oliprevin
- Pravastatinum
- Vasten
- Pravastatin Sodium Salt
- Pravastatina [Spanish]
- Pravastatine [French]
- Pravastatinum [Latin]
- KS-5015
- Pravachol (TN)
- Pravastatin (INN)
- Pravastatin [INN:BAN]
- Pravastatin tert-Octylamine Salt
- Pravator (TN)
- RMS-431
- Selektine (TN)
- SQ-31,000
- KXO2KT9N0G
- CHEBI:63618
- Pravastatinum (Latin)
- Apo Pravastatin
- Lin Pravastatin
- Nu Pravastatin
- RefChem:56363
- DTXCID003498
Reported adverse events
- Hypersensitivity
- Cough
- Headache
- Myalgia
- Myopathy
- Rash
- Vomiting
- Dizziness
- Fatigue
- Nausea
- Stevens-Johnson syndrome
- Influenza
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