← SynDRA

MIGALASTAT

SynDRA canonical compound SYN0004048 — structure-anchored drug synonym record

All known targets

• GLA
• AGL
• GAA
• GBA2
• GLB1
• Glb1
• LCT
• Lct
• MGAM
• SI
• aglC
• lacZ

Mechanisms of action (all sources)

• GLA STABILISER
• Alpha-galactosidase A stabiliser
• alpha-galactosidase a inhibitor
• GLA MODULATOR
• GLA PHARMACOLOGICAL CHAPERONE

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• GBA1
• MAOA
• HRH3
• HTR1A
• HTR2B
• KCNH2
• KDR
• MAN2B1
• MAN2B2
• MANBA
• OPRM1
• ADORA1
• PDE3A
• PDE4A
• PGR
• PTGS1
• SLC6A2
• SLC6A3
• SLC6A4
• TBXA2R
• GBA3
• ACHE
• GANAB
• FUCA1
• ADORA3
• ADRA1A
• ADRA2A
• ALOX15
• APEX1
• AR
• CHRM1
• CHRM2
• CYP1A2
• CYP2C19
• CYP2C9
• CYP2D6
• CYP3A4
• DRD1
• DRD3
• ESR1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• LYAG

ATC classes

• A16A · OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS

Cross-references

• PubChem CID: 176077
• ChEMBL: CHEMBL110458
• DrugBank: DB05018
• ChEBI: CHEBI:135923
• KEGG: D10359
• RxNorm: 2054252
• PDB: DGJ
• Wikipedia: Migalastat
• TTD: D0MU9L

Synonyms

• GALAFOLD
• Galafold
• migalastat HCl
• GR181413A
• 1-Deoxygalactonojirimycin hydrochloride
• 1-Deoxygalactonojirimycin
• migalastat hydrochloride
• galafold
• At-1001, gr-181314a
• DDIG
• D-Galactitol, 1,5-dideoxy-1,5-imino
• 1,5-Dideoxy-1,5-iminogalactitol
• 2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride
• C4XNY919FW
• 1-deoxygalactonojirimycin
• 1-Deoxygalactostatin
• migalastatum
• RefChem:56444
• 1-deoxygalacto-nojirimycin
• A16AX14
• DTXCID401507205
• NB-DGJ
• 1,5-Dideoxy-1,5-imino-D-galactitol
• Migalastat [INN]
• Migalastat [USAN:INN]
• UNII-C4XNY919FW
• DGJ
• NSC658776
• Tocris-1258
• MIGALASTAT [MI]
• Migalastat (USAN/INN)
• MIGALASTAT [USAN]
• MIGALASTAT [WHO-DD]
• D-galacto-1-Deoxynojirimycin
• orb1737999
• SCHEMBL29355275
• GTPL10200
• CHEBI:135923

Reported adverse events

• Abdominal pain
• Epistaxis
• Headache
• Nausea
• Back pain
• Cough
• Nasopharyngitis
• Pyrexia
• Urinary tract infection