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SOBETIROME
SynDRA canonical compound SYN0004025 — structure-anchored drug synonym record
| Clinical phase | Phase 1/Phase 2 |
|---|
| Primary target(s) | THRB |
|---|
| Mechanism of action | Thyroid hormone receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- Thyroid hormone receptor agonist
- THRA AGONIST
- THRB AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HDAC6
- HNF4A
- MBD4
- NEIL1
- NEIL2
- NR2C1
- NR2E1
- NR4A1
- NR5A1
- NTHL1
- OGG1
- RXRA
- SMUG1
- TDG
- UNG
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Sobetiroma
- GC-1
- QRX-431
- GC 1
- QRX 431
- CHEMBL107400
- CHEBI:79988
- 2-(4-(4-hydroxy-3-isopropylbenzyl)-3,5-dimethylphenoxy)acetic acid
- XQ31741E9Q
- 2-[4-[(4-hydroxy-3-propan-2-ylphenyl)methyl]-3,5-dimethylphenoxy]acetic acid
- Sobetirome (USAN)
- SOBETIROME [USAN]
- {4-[4-Hydroxy-3-(1-Methylethyl)benzyl]-3,5-Dimethylphenoxy}acetic Acid
- Gc 1 Compound
- GC-1;QRX-431
- [4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-phenoxy]-acetic acid
- 2-[4-[[4-Hydroxy-3-(1-methylethyl)phenyl]methyl]-3,5-dimethylphenoxy]acetic acid
- Acetic acid, 2-[4-[[4-hydroxy-3-(1-methylethyl)phenyl]methyl]-3,5-dimethylphenoxy]-
- 3imy
- B72
- SOBETIROME [INN]
- Sobetirome [USAN:INN]
- SOBETIROME [WHO-DD]
- SCHEMBL282119
- UNII-XQ31741E9Q
- GTPL2639
- DTXSID60891557
- GC-1; QRX-431
- BCP23779
- BDBM50115668
- ZINC13475083
- AKOS024458221
- CS-0956
- DB07425
- BS-42167
- HY-14823
- DB-066428
- FT-0735243
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