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DICYCLOMINE
SynDRA canonical compound SYN0003910 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CHRM2 |
|---|
| Mechanism of action | Acetylcholine receptor antagonist |
|---|
| Indication | irritable bowel syndrome |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- CHRM1
- CHRM3
- CHRM2
- CHRM4
- HTR6
- SIGMAR1
- SCN3A
- SCN2A
- SCN1A
- Pgrmc1
- KCNH2
- HTR2B
Mechanisms of action (all sources)
- Acetylcholine receptor antagonist
- CHRM3 ANTAGONIST
- Muscarinic acetylcholine receptor M3 antagonist
- CHRM1 ANTAGONIST
- Muscarinic acetylcholine receptor M1 antagonist
- CHRM2 ANTAGONIST
- CHRM4 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD1
- NR1I2
- ABCB11
- OPRD1
- NR3C1
- NPY2R
- NPY1R
- NPSR1
- MPHOSPH8
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- OPRM1
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- HTR3A
- HTR1A
- HSD17B10
- HRH3
- OPRK1
- PDE3A
- HMGCR
- SLC6A2
- TSHR
- THPO
- TDP1
- TBXAS1
- TACR2
- TACR1
- SMPD1
- SLCO1B3
- SLCO1B1
- SLC6A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ACM2
- ACM4
- ACM5
- CP19A
- CP1A2
- CP2D6
- CP3A4
- CP3A7
- JUN
- RARA
- SMAD2
- SMAD3
Drug classes
- Cholinergic Antagonists
- Anticholinergic
- Cholinergic Agents
- Muscarinic Antagonists
- Neurotransmitter Agents
- Parasympatholytics
- Peripheral Nervous System Agents
ATC classes
- A03A · DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Cross-references
Synonyms
- BENTYL
- BENTYL PRESERVATIVE FREE
- Bentyl
- DICYCLOMINE HYDROCHLORIDE
- DICYCLOMINE HYDROCHLORIDE (PRESERVATIVE FREE)
- dicycloverine
- dicymine
- dicycloverine hydrochloride
- dicycloverin
- dicyclomine hydrochloride
- dicyclomine HCl
- Dicycloverine
- Dicicloverina
- Dicymine
- Kolantyl
- Atumin
- Bentomine
- Bentylol
- Dicycloverin
- Dicycloverinum
- Diocyl
- Dyspas
- Formulex
- Mamiesan
- Merbentyl
- Procyclomin
- Sawamin
- Spasmoban
- Wyovin
- Bentyl hydrochloride
- Bentylol hydrochloride
- Dicyclomine Hcl
- Dicycloverin hydrochloride
- Diethylaminocarbethoxybicyclohexyl hydrochloride
- Diocyl hydrochloride
- Kolantyl hydrochloride
- Wyovin hydrochloride
Reported adverse events
- Asthenia
- Dizziness
- Nausea
- Nervousness
- Somnolence
- Vision blurred
- Nervous system disorder
- Abdominal distension
- Confusional state
- Cycloplegia
- Dermatitis
- Dermatitis allergic
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