← SynDRA
IDARUBICIN
SynDRA canonical compound SYN0003829 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | TOP2A |
|---|
| Mechanism of action | Topoisomerase inhibitor |
|---|
| Indication | acute myeloid leukemia (AML) |
|---|
| Disease area | hematologic malignancy |
|---|
All known targets
Mechanisms of action (all sources)
- topoisomerase inhibitor
- TOP2A INHIBITOR
- DNA topoisomerase II alpha inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR2C
- HRH1
- NR3C1
- DRD1
- ESR1
- ESR2
- SLC6A4
- SOS1
- GHSR
- SLC6A2
- PGR
- ADRA2C
- KCNH2
- NR1I2
- MPHOSPH8
- MTOR
- NPC1
- NPY1R
- NPY2R
- KAT2A
- MMP1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- MMP9
- LMNA
- MAOA
- MC5R
- KDM4A
- KDM4E
- MC4R
- PDE5A
- MC3R
- KMT2A
- MBNL1
- MAPT
- MAPK3
- LCK
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 1433G
- MDR1
- PADI4
- OXYR
- NSD2
- NR1H4
- NF2L2
- MUS81
- MDM4
- IFNG
- MDM2
- MCL1
- M4K2
- LYPA1
- KSYK
- KCNQ1
- PAFA
- PPARD
- PPARG
- PPCEL
- PPME1
- PRGR
- RARA
- RGS12
- RPGF3
- RPGF4
- SIRPA
- SMAD2
- SYK
- THB
- TP53
- TSHR
- UBP1
- IL1B
- IFNB1
- ABC3A
- CCDC88A
- CP3A4
- CP2D6
- CP19A
Drug classes
- Topoisomerase Inhibitors
- Anthracycline Topoisomerase Inhibitor
- Antibiotics, Antineoplastic
- Antineoplastic Agents
- Enzyme Inhibitors
- Topoisomerase II Inhibitors
ATC classes
- L01D · CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
Cross-references
Synonyms
- IDAMYCIN
- IDAMYCIN PFS
- IDARUBICIN HYDROCHLORIDE
- Idamycin
- 4-Demethoxydaunomycin
- 4-Demethoxydaunorubicin
- demethoxydaunorubicin
- idarubicin hydrochloride
- idarubicin HCl
- Idarubicine
- Idarubicina
- DMDR
- Idarubicinum
- Zavedos
- Idarubicin Hcl
- Idarubicin Hcl Pfs
- Idarubicin hydrochloride
- DM5
- I 1656
- IMI-30
- Idamycin (TN)
- Idarubicin (INN)
- Idarubicin [INN:BAN]
- Idarubicina [INN-Spanish]
- Idarubicine [INN-French]
- Idarubicinum [INN-Latin]
- Zavedos (TN)
- 4-DMD
- 4-Desmethoxydaunorubicin
- NSC 256439
- ZRP63D75JW
- CHEBI:42068
- IDARUBICIN [INN]
- Idarubicinhydrochloride
- MLS001401448
- Daunomycin, 4-demethoxy-
- NSC256439
Look up IDARUBICIN in the interactive SynDRA portal →