← SynDRA
BISPHENOL A
SynDRA canonical compound SYN0003796 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | PPARG |
|---|
| Mechanism of action | Estrogen receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- ESR1 AGONIST
- AR ANTAGONIST
- ESR2 PARTIAL AGONIST
- ESR2 AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR6
- ACHE
- NFE2L2
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KRAS
- KCNH2
- HTR2C
- HTR2B
- HTR2A
- HSD17B10
- HRH2
- HRH1
- HRAS
- HPGD
- HMGCR
- HDAC6
- GSK3B
- GLS
- GLP1R
- MMP9
- NPY1R
- ADORA1
- NPY2R
- TSHR
- THRB
- TDP1
- TBXAS1
- TACR2
- TACR1
- SULT1C4
- SLC6A4
- SLC6A3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- KSYK
- SYK
- SMAD3
- SMAD2
- RPGF4
- RAPGEF4
- PRGR
- PPARD
- PA1B2
- NR1I2
- NF2L2
- GPR32
- AHR
- GLI3
- GCR
- ESRRA
- CP3A7
- CP3A4
- CP2D6
- CP2C9
- CP1A2
- ANDR
- ALR
- TOR1A
Drug classes
- Air Pollutants, Occupational
- Estrogens, Non-Steroidal
- Free Radical Scavengers
- synthetic estrogen
Cross-references
Synonyms
- BPA
- bisphenol-a
- 2,2-Bis(4-hydroxyphenyl)propane
- Bisphenol
- Diano
- 4,4'-Isopropylidenediphenol
- 4,4'-(propane-2,2-diyl)diphenol
- Diphenylolpropane
- 4,4'-bisphenol-A
- 2,2-Bis(p-hydroxyphenyl)propane
- Parabis A
- DIAN
- Rikabanol
- Biphenol A
- Ipognox 88
- p,p'-Bisphenol A
- Pluracol 245
- Bisferol A
- p,p'-Isopropylidenebisphenol
- 2,2-Di(4-phenylol)propane
- 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol
- p,p'-Dihydroxydiphenylpropane
- 4,4'-(1-Methylethylidene)bisphenol
- 4,4'-Dihydroxydiphenylpropane
- Ucar bisphenol A
- Dimethylmethylene-p,p'-diphenol
- p,p'-Isopropylidenediphenol
- Bis(4-hydroxyphenyl)propane
- Ucar bisphenol HP
- Phenol, 4,4'-(1-methylethylidene)bis-
- 2,2-Di(4-hydroxyphenyl)propane
- 4,4'-ISOPROPYLIDENE-DIPHENOL
- 2,2-Bis(hydroxyphenyl)propane
- p,p'-Dihydroxydiphenyldimethylmethane
- 4,4'-Isopropylidenebisphenol
- Bis(4-hydroxyphenyl)dimethylmethane
- Isopropylidenebis(4-hydroxybenzene)
Look up BISPHENOL A in the interactive SynDRA portal →