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SULFAPHENAZOLE
SynDRA canonical compound SYN0003771 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | DHPS |
|---|
| Mechanism of action | Dihydropteroate synthetase inhibitor |
|---|
| Indication | urinary tract infections |
|---|
| Disease area | infectious disease |
|---|
All known targets
Mechanisms of action (all sources)
- Dihydropteroate synthetase inhibitor
- CYP2C9 INHIBITOR
- CYP2C9 MODULATOR
- folP INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- OPRD1
- NPY2R
- NPY1R
- NPSR1
- NFKB1
- NFE2L2
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HSD17B10
- HRH2
- HRH1
- HMGCR
- NR3C1
- OPRK1
- ADORA1
- OPRM1
- USP1
- TSHR
- THPO
- TDP1
- TBXAS1
- TACR2
- TACR1
- SMAD3
- SLCO2B1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
ATC classes
- J01E · SULFONAMIDES AND TRIMETHOPRIM
- S01A · ANTIINFECTIVES
Cross-references
Synonyms
- SULFABID
- sulfabid
- sulfaphenazol
- sulfaphenazon
- sulfaphenylpyrazole
- sulphaphenazole
- sulfafenazol
- Sulfafenazol
- Sulfaphenazol
- NSC-757859
- Orisulf
- Sulfabid
- Sulphaphenazole
- Sulfaphenazolum
- Sulfafenazolo
- 1-Phenyl-5-sulfanilamidopyrazole
- 5-Sulfanilamido-1-phenylpyrazole
- Sulfaphenylpyrazol
- Phenylsulfapyrazole
- N'-(1-Phenylpyrazol-5-yl)sulfanilamide
- 3-(p-Aminobenzenesulfonamido)-2-phenylpyrazole
- N(sup 1)-(1-Phenylpyrazol-5-yl)sulfanilamide
- NSC 757859
- N(1)-(1-Phenylpyrazol-5-yl)sulfanilamide
- 0J8L4V3F81
- DTXCID0024131
- CHEBI:77780
- RefChem:57550
- J01ED08
- Sulfaphenazon
- Depocid
- Sulphenazole
- Plisulfan
- Raziosulfa
- Sulfaphenylpyrazole
- Depotsulfonamide
- Sulfaphenylpipazol
- Paidazolo
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