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EPOTHILONE D
SynDRA canonical compound SYN0003765 — structure-anchored drug synonym record
Clinical phase
Phase 2
Primary target(s)
TUBB
Mechanism of action
microtubule stabilizing agent | tubulin polymerization inhibitor
All known targets
TUBB
TUBA1A
TUBA1B
TUBA1C
TUBA3C
TUBA3E
TUBA4A
TUBB1
TUBB2A
TUBB2B
TUBB3
TUBB4A
Mechanisms of action (all sources)
TUBB4B STABILISER
TUBB1 STABILISER
TUBA3C STABILISER
TUBA4A STABILISER
TUBB3 STABILISER
TUBA1A STABILISER
TUBB4A STABILISER
TUBB8 STABILISER
TUBB STABILISER
TUBA1B STABILISER
TUBA1C STABILISER
TUBA3E STABILISER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
ABCB1
HDAC6
Cross-references
PubChem CID:
447865
ChEMBL:
CHEMBL96172
DrugBank:
DB01873
ChEBI:
29579
KEGG:
C12039
PDB:
EPD
TTD: D0N4OZ
Synonyms
(-)-desoxyepothilone b
12,13-desoxyepothilone b
12,13-desoxyepothilone b, cis
Desoxyepothilone b
KOS-862
NSC-703147
R-1492
R1492
(-)-Desoxyepothilone B
KOS 862
12,13-Desoxyepothilone B
UNII-T0358E0YUF
(-)-Epothilone D
NSC 703147
T0358E0YUF
CHEBI:29579
12,13-Deoxyepothilone B
Epo D
EPD
(4S,7R,8S,9S,16S,Z)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-((E)-1-(2-methylthiazol-4-yl)prop-1-en-2-yl)oxacyclohexadec-13-ene-2,6-dione
(4S,7R,8S,9S,13Z,16S)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(E)-1-methyl-2-(2-methylthiazol-4-yl)vinyl]-1-oxacyclohexadec-13-ene-2,6-dione
dEpoB
Utidelone
Epothilon D
Epothiolone D
DEpoB cpd
Epothilone B, desoxy
KOS862
NSC703147
RefChem:137339
DTXCID901022595
MFCD27976357
Epothilone D (synthetic)
utidelone [INN]
EPOTHILONE D [MI]
SCHEMBL4415
Z-12,13-desoxyepothilone B
EPOTHILONE D [WHO-DD]
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