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HALOFANTRINE
SynDRA canonical compound SYN0003758 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | CYP3A5 | KCNN4 |
|---|
| Mechanism of action | antimalarial agent |
|---|
| Indication | malaria |
|---|
| Disease area | infectious disease |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- CACNA1C
- ADORA1
- MC3R
- OPRD1
- NR3C1
- NPY1R
- NFE2L2
- MLNR
- MAOA
- OPRM1
- LMNA
- IDH1
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- OPRK1
- PDE3A
- HRH3
- SLC6A3
- UBE2N
- TDP1
- TARDBP
- SNCA
- SMPD1
- SLC6A4
- SLC6A2
- PDE4D
- SLC29A1
- SCN5A
- SAMHD1
- PTGS2
- PPARG
- PGR
- HSP90AA1
- HRH2
- ADORA2A
- HRH1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- APAF
- IDHC
- RARA
- PPP1CA
- NSD2
- MDM4
- MDM2
- KSYK
- IFNG
- HS90A
- CACNA1D
- GPR32
- ESRRA
- CP3A7
- CP3A4
- CP2D6
- CACNA1S
- CACNA1F
- SYK
Drug classes
- Antimalarial
- Anti-Infective Agents
- Antimalarials
- Antiparasitic Agents
- Antiprotozoal Agents
- antimalarial agent
ATC classes
Cross-references
Synonyms
- HALFAN
- halofantrine hydrochloride
- halfan
- halofantrine HCl
- Halofantrina
- DL-WR-171669
- Halfan
- Halofantrino
- HALOFANTRINE HYDROCHLORIDE
- Halofantrine HCl
- Halofantrine Hydrochloride [USAN]
- Halofantrine [USAN]
- Halofantrino [Spanish]
- WR-171669
- Dl-WR 171669
- Halfan (TN)
- Halofantrine hydrochloride (USAN)
- WR 171,699
- WR-171699
- SK&F-102866
- WR-171,669
- (+-)-Halofantrine hydrochloride
- (1)-Halofantrine
- Halofantrine, (-)-
- Halofantrinum [INN-Latin]
- Halofantrina [INN-Spanish]
- Halofantrinum
- Q2OS4303HZ
- Halofantrine (INN)
- HALOFANTRINE [INN]
- (-)-Halofantrine
- EINECS 274-104-1
- MLS002154111
- Halofantrine, (R)-
- Halofantrine, (+)-
- R7ADS21FSN
- SMR001233418
- UNII-Q2OS4303HZ
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