← SynDRA

LIDOFLAZINE

SynDRA canonical compound SYN0003702 — structure-anchored drug synonym record

All known targets

• SLC29A1
• SCN3A
• KCNH2
• SCN1A
• Scn1a
• Scn2a
• Scn3a

Mechanisms of action (all sources)

• calcium channel blocker
• SCN3A INHIBITOR
• SLC29A1 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• SLC6A3
• DRD3
• HRH1
• ADRA1A
• ADRA2A
• ADRA2B
• ADRA2C
• HTR2A
• HTR2B
• SLC6A4
• OPRK1
• SLC6A2
• DRD1
• DRD2
• MC3R
• LMNA
• ADORA1
• KDM4A
• IDH1
• HTR3A
• NPY1R
• HTR2C
• MLNR
• OPRM1
• NR1I2
• NR3C1
• OPRD1
• HRH3
• PDE3A
• PDE4D
• PGR
• PTGS2
• PTH1R
• SAMHD1
• SMAD3
• TBXA2R
• TDP1
• USP1
• HTR1A
• GMNN

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• 5HT2A
• ANDR
• RARA
• NSD2
• MDR1
• MDM4
• MDM2
• KSYK
• IL1B
• ESRRA
• CP3A7
• CP2D6
• CP2CJ
• CP2C9
• BRCA1
• BARD1
• APAF
• SYK

Drug classes

• Calcium Channel Blockers
• Calcium-Regulating Hormones and Agents
• Cardiovascular Agents
• Membrane Transport Modulators
• Vasodilator Agents

ATC classes

• C08E · NON-SELECTIVE CALCIUM CHANNEL BLOCKERS

Cross-references

• PubChem CID: 3926
• ChEMBL: CHEMBL92870
• DrugBank: DB13766
• ChEBI: CHEBI:93095
• KEGG: D04733
• RxNorm: 6390
• Wikipedia: Lidoflazine
• TTD: D0L7VL
• LINCS BRD: BRD-K62996583

Synonyms

• corflazine
• lidoflazin
• lidoflazinum
• ordiflazine
• Lidoflazina
• MCN-JR-7904
• R-7904
• Angex
• Clinium
• Ordiflazine
• Corflazine
• Lidoflazinum
• Lidoflazin
• Klinium
• Lidoflazina [Italian]
• UNII-J4ZHN3HBTE
• Lidoflazinum [INN-Latin]
• Lidoflazina [INN-Spanish]
• Lidoflazine [USAN:INN:BAN]
• C30H35F2N3O
• J4ZHN3HBTE
• EINECS 222-312-8
• R 7904
• BRN 0904339
• CHEMBL92870
• 4-(4,4-Bis(p-fluorophenyl)butyl)-1-piperazineaceto-2',6'-xylidide
• 1-Piperazineacetamide, 4-(4,4-bis(4-fluorophenyl)butyl)-N-(2,6-dimethylphenyl)-
• NCGC00016627-01
• NCGC00016627-04
• CAS-3416-26-0
• McN-JR 7904
• DTXCID4025377
• RefChem:389096
• C08EX01
• Lidoflazine.5%
• Prestwick_700
• Angex (TN)