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ETHOTOIN
SynDRA canonical compound SYN0003680 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · OTC |
| Primary target(s) | SCN5A |
| Mechanism of action | Hydantoin antiepileptic |
| Indication | seizures |
| Disease area | neurology/psychiatry |
All known targets
- SCN5A
- SCN10A
- SCN11A
- SCN1A
- SCN2A
- SCN3A
- SCN4A
- SCN7A
- SCN8A
- SCN9A
Mechanisms of action (all sources)
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
- SCN10A BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- HRH2
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- IDH1
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PPARG
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- HRH3
- HRH1
- ADORA2A
- HDAC6
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
Drug classes
- Anticonvulsants
- Cardiovascular Agents
- Central Nervous System Agents
- Membrane Transport Modulators
- Sodium Channel Blockers
- Voltage-Gated Sodium Channel Blockers
- Anti-epileptic Agent
- Hydantoin antiepileptic
ATC classes
Cross-references
Synonyms
- PEGANONE
- accenon
- peganone
- Ethotoine
- Etotoina
- Accenon
- NSC-760074
- Peganone
- Ethotoinum
- Pegoanone
- Abbott brand of ethotoin
- Accenon (TN)
- Ethotoine [INN-French]
- Ethotoinum [INN-Latin]
- Etotoina [INN-Spanish]
- Peganone (TN)
- Ethotoin [INN:BAN:JAN]
- Ethotoin (JAN/USP/INN)
- (+-)-3-Ethyl-5-phenylhydantoin
- 3-Ethyl-5-phenylhydantoin
- Hydantoin, 3-ethyl-5-phenyl-
- NSC 760074
- CHEBI:4888
- DTXCID903020
- RefChem:56515
- N03AB01
- AC-695; Accenon
- (+/-)-3-ethyl-5-phenylhydantoin
- HSDB 3580
- EINECS 201-665-1
- MFCD00072127
- BRN 0188272
- UNII-46QG38NC4U
- Ethotoin [USP:INN:BAN:JAN]
- CAS-86-35-1
- NCGC00016340-01
- Ethotoin (Standard)
- ETHOTOIN [HSDB]
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