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FELBAMATE
SynDRA canonical compound SYN0003679 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | GRIN2B |
|---|
| Mechanism of action | Glutamate receptor antagonist |
|---|
| Indication | epilepsy |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- GRIN2A
- GRIN2B
- GRIN3A
- GRIN1
- GRIN2C
- GRIN2D
- GRIN3B
Mechanisms of action (all sources)
- Glutamate receptor antagonist
- GRIN1 ANTAGONIST
- GRIN2A ANTAGONIST
- GRIN2B ANTAGONIST
- GRIN2D ANTAGONIST
- GRIN3B ANTAGONIST
- GRIN2C ANTAGONIST
- GRIN3A ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD1
- ADORA1
- NR3C1
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MC4R
- MLNR
- NFE2L2
- NPSR1
- NPY1R
- NR1I2
- OPRD1
- HRH2
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PKM
- PTGS2
- RAPGEF3
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SMN1
- TBXA2R
- HTR1A
- HRH1
- ADORA2A
- HDAC6
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anticonvulsants
- Central Nervous System Agents
- Excitatory Amino Acid Antagonists
- Neurotransmitter Agents
- Anti-epileptic Agent
ATC classes
Cross-references
Synonyms
- FELBATOL
- Felbatol
- felbamyl
- felbatol
- Felbamato
- ADD-03055
- NSC-759866
- W-554
- Taloxa
- Felbamatum
- Felbamyl
- Essex brand of felbamate
- Felbamato [Spanish]
- Felbamatum [Latin]
- Schering brand of felbamate
- F 0778
- Wallace brand 1 of felbamate
- Wallace brand 2 of felbamate
- Carbamic acid 2-phenyltrimethylene ester
- Felbamate [USAN:INN]
- Felbatol (TN)
- Schering-Plough brand of felbamate
- Carbamic acid, 2-phenyltrimethylene ester
- Felbamate (USAN/INN)
- (3-carbamoyloxy-2-phenyl-propyl) carbamate
- (3-carbamoyloxy-2-phenylpropyl) carbamate
- 1,3-Propanediol, 2-phenyl-, dicarbamate
- 2-Phenyl-1,3-propanediol dicarbamate
- 2-Phenylpropane-1,3-diyl dicarbamate
- W 554
- ADD 03055
- carbamic acid 2-phenyltrimethylene ester
- CHEBI:4995
- NSC 759866
- 3-(carbamoyloxy)-2-phenylpropyl carbamate
- MLS000028465
- X72RBB02N8
Reported adverse events
- GH
- Acne
- Agitation
- Anxiety
- Ataxia
- Constipation
- Cough
- Depression
- Diplopia
- Dizziness
- Dyspepsia
- Dystonia
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