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MEPIVACAINE
SynDRA canonical compound SYN0003643 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SCN9A |
|---|
| Mechanism of action | potassium channel blocker | sodium channel blocker |
|---|
| Indication | local anesthetic |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SCN9A
- SCN1A
- SCN2A
- SCN3A
- SCN4A
- SCN5A
- SCN8A
- SCN10A
- SCN11A
- SCN7A
Mechanisms of action (all sources)
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
- SCN10A BLOCKER
- potassium channel blocker
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- MAPK14
- NR3C1
- NR1I2
- NPY2R
- NPY1R
- NFE2L2
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK1
- OPRK1
- MAOB
- MAOA
- LCK
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- OPRD1
- OPRM1
- ADORA1
- SAMHD1
- TDP1
- TBXAS1
- TARDBP
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anesthetics
- Anesthetics, Local
- Central Nervous System Agents
- Central Nervous System Depressants
- Peripheral Nervous System Agents
- Sensory System Agents
- Amide Local Anesthetic
ATC classes
- N01B · ANESTHETICS, LOCAL
Cross-references
Synonyms
- ARESTOCAINE HYDROCHLORIDE
- ARESTOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN
- CARBOCAINE
- CARBOCAINE W/ NEO-COBEFRIN
- Carbocaine
- ISOCAINE HYDROCHLORIDE
- ISOCAINE HYDROCHLORIDE W/ LEVONORDEFRIN
- MEPIVACAINE HYDROCHLORIDE
- MEPIVACAINE HYDROCHLORIDE W/ LEVONORDEFRIN
- POLOCAINE
- POLOCAINE W/ LEVONORDEFRIN
- POLOCAINE-MPF
- (+/-)-Mepivacaine
- carbocain
- carbocaine
- DL-Mepivacaine
- mepicaine
- tevacaine
- mepivacaine hydrochloride
- mepivacaine HCl
- scandonest
- Mepivacaina
- 1-methyl-2',6'-pipecoloxylidide
- 2',6'-pipecoloxylidide, 1-methyl-
- Carboplyin dental
- Dl-mepivacaine
- Mepisv
- Tevacaine
- APF-135
- Mepivacainum
- Mepivicaine
- Scandicain
- Scandicaine
- Scandicane
- Arestocaine HCL
- Carboplyin Dental
- Isocaine HCL
- Carbocaine (TN)
Reported adverse events
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