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MASOPROCOL
SynDRA canonical compound SYN0003582 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | ALOX5 | IGF1R |
|---|
| Mechanism of action | lipoxygenase inhibitor |
|---|
| Indication | actinic keratosis (AK) |
|---|
| Disease area | dermatology |
|---|
All known targets
- IGF1R
- ALOX5
- ERBB2
- ALOX12
- mex-5
- TTR
- TRPA1
- SNCA
- PTGS2
- PTGS1
- LTB4R
- LOX1.1
Mechanisms of action (all sources)
- ERBB2 INHIBITOR
- Receptor protein-tyrosine kinase erbB-2 inhibitor
- IGF1R INHIBITOR
- Insulin-like growth factor I receptor inhibitor
- lipoxygenase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- MPHOSPH8
- OPRM1
- OPRK1
- OPRD1
- NR3C1
- NR1I2
- NPY1R
- NFKB1
- NFE2L2
- MTOR
- MLNR
- HTR2B
- MC4R
- MC3R
- MAPK1
- MAOA
- LMNA
- KDM4E
- KCNH2
- KAT2A
- HTR3A
- PDE3A
- PDE4D
- PGR
- PIN1
- USP2
- USP1
- TP53
- THPO
- TDP1
- TBXA2R
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- RGS4
- RECQL
- RAB9A
- PPARG
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antioxidants
- Antirheumatic Agents
- Cyclooxygenase Inhibitors
- Enzyme Inhibitors
- Lipoxygenase Inhibitors
- Peripheral Nervous System Agents
- Protective Agents
- Sensory System Agents
ATC classes
- L01X · OTHER ANTINEOPLASTIC AGENTS
Cross-references
Synonyms
- nordihydroguaiaretic acid
- actinex
- mesonordihydroguaiaretic acid
- Nordihydroguaiaretic acid
- Dihydronorguaiaretic acid
- Dinorguaiaretic acid, dihydro-
- Insm-18
- Insm18
- Meso-nordihydroguaiaretic acid
- Nordihydroguaiaretate
- Nordihydroguiaretic acid
- Oristar nhga
- CHX-100
- MESO-NDGA
- NSC-4291
- NSC-682984
- Actinex
- NDGA
- N 5023
- TNP00263
- Actinex (TN)
- Nordihydroguaiaretic acid (meso-form)
- (R*,S*)-4,4'-(2,3-Dimethylbutane-1,4-diyl)bispyrocatechol
- 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
- meso-NDGA
- meso Nordihydroguaiaretic Acid
- Masoprocolum
- meso-4,4'-(2,3-Dimethyltetramethylene)dipyrocatechol
- ORISTAR NHGA
- 7BO8G1BYQU
- INSM-18
- erythro-nordihydroguaiaretic acid
- DTXCID3025178
- CHEBI:73468
- meso-2,3-bis(3,4-dihydroxyphenylmethyl)butane
- meso-1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane
- meso-4,4'-(2,3-dimethyl-1,4-butanediyl)bis(pyrocatechol)
- Acid, meso-Nordihydroguaiaretic
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