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CIFENLINE
SynDRA canonical compound SYN0003521 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Mechanism of action | sodium channel blocker |
|---|
| Indication | cardiac arrythmia |
|---|
| Disease area | cardiology |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SCN5A
- ESR1
- ACHE
- HTR1A
- SLC6A4
- SLC6A3
- SLC6A2
- PTGS1
- PGR
- PDE4A
- PDE3A
- OPRM1
- MAOA
- KDR
- HTR2B
- HRH3
- ADORA3
- F2
- DRD3
- DRD1
- CYP3A4
- CHRM2
- CHRM1
- CACNA1C
- ATXN2
- ARSA
- AR
- ADRA2A
- ADRA1A
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- SCN10A
- SCN11A
- SCN1A
- SCN2A
- SCN3A
- SCN4A
- SCN7A
- SCN8A
- SCN9A
Drug classes
- Anti-Arrhythmia Agents
- Cardiovascular Agents
ATC classes
- C01B · ANTIARRHYTHMICS, CLASS I AND III
Cross-references
Synonyms
- cibenzoline
- (RS)-Cibenzoline
- (+/-)-Cibenzoline
- cibenzoline succinate
- cifenline succinate
- Cibenzoline
- Cibenzolina
- RO-22-7796
- 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-1H-imidazole
- Cibenzolinum
- Cifenline [USAN]
- Cibenzoline [INN]
- CHEMBL87045
- Cibenzoline (INN)
- Cifenline (USAN)
- Z7489237QT
- Cifenline; Ro 22-7796; UP 33-901
- 2-(2,2-Diphenyl-cyclopropyl)-4,5-dihydro-1H-imidazole
- Cibenzolinum [INN-Latin]
- Cibenzolina [INN-Spanish]
- 2-(2,2-diphenylcyclopropyl)-2-imidazoline
- NCGC00162222-01
- EINECS 258-453-7
- Ro 227796
- UP 33901
- UNII-Z7489237QT
- (+-)-2-(2,2-Diphenylcyclopropyl)-2-imidazoline
- CIFENLINE [MI]
- CIBENZOLINE [MART.]
- CIBENZOLINE [WHO-DD]
- SCHEMBL122806
- DTXSID9022819
- CHEBI:135083
- 1H-Imidazole, 2-(2,2-diphenylcyclopropyl)-4,5-dihydro-, (+-)-
- BDBM50151856
- MFCD00864706
- AKOS016013956
- DB13358
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