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MORICIZINE
SynDRA canonical compound SYN0003520 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | SCN5A |
|---|
| Mechanism of action | Sodium channel blocker |
|---|
| Indication | ventricular arrhythmias |
|---|
| Disease area | cardiology |
|---|
All known targets
- SCN5A
- SCN10A
- SCN11A
- SCN1A
- SCN2A
- SCN3A
- SCN4A
- SCN7A
- SCN8A
- SCN9A
Mechanisms of action (all sources)
- Sodium channel blocker
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
- SCN10A BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- PDE4D
- ADORA1
- MC3R
- MAOA
- LMNA
- KCNH2
- KAT2A
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HIF1A
- MAPK1
- NPY1R
- MLNR
- ADORA2A
- NR3C1
- OPRD1
- OPRK1
- PDE3A
- PGR
- PPARG
- PTGS2
- PTH1R
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SMN1
- HDAC6
- GNAS
- GMNN
- AGTR1
- CCKBR
- CCKAR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- ANDR
- CP2C9
- CP2CJ
- CP3A4
- CP3A7
- NF2L2
Drug classes
- Antiarrhythmic
- Anti-Arrhythmia Agents
- Cardiovascular Agents
- Membrane Transport Modulators
- Sodium Channel Blockers
- Voltage-Gated Sodium Channel Blockers
ATC classes
- C01B · ANTIARRHYTHMICS, CLASS I AND III
Cross-references
Synonyms
- ETHMOZINE
- moracizine
- moricizine hydrochloride
- ethmozine
- moricizine HCl
- Moracizine
- Moracizina
- EN-313
- EN-313 FREE BASE
- Moracizin
- Moracizinum
- Moricizine [USAN]
- G 214
- Moracizina [INN-Spanish]
- Moracizine (INN)
- Moracizinum [INN-Latin]
- Moricizine (USAN)
- 2GT1D0TMX1
- CHEBI:6997
- RefChem:819399
- DTXCID803335
- C01BG01
- EN313
- EN 313
- C22H25N3O4S
- Moracizine [INN]
- NCGC00016809-01
- NCGC00016809-07
- EINECS 250-854-5
- UNII-2GT1D0TMX1
- MFCD00336543
- MORICIZINE [MI]
- Prestwick0_001051
- Prestwick1_001051
- Prestwick2_001051
- Prestwick3_001051
- MORICIZINE [VANDF]
- MORACIZINE [MART.]
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