← SynDRA
CLOMETHIAZOLE
SynDRA canonical compound SYN0003517 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | GABRA1 |
|---|
| Mechanism of action | GABA receptor antagonist |
|---|
| Indication | muscle relaxant | Parkinson's Disease | sedative |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- GABRA1
- GABRB3
- GABRG2
- GABRG3
- GABRA2
- GABRA3
- GABRA4
- GABRA5
- GABRA6
- GABRB1
- GABRB2
- GABRD
Mechanisms of action (all sources)
- GABA receptor modulator
- GABA receptor antagonist
- GABRA1 POSITIVE ALLOSTERIC MODULATOR
- GABRB2 POSITIVE ALLOSTERIC MODULATOR
- GABRG2 POSITIVE ALLOSTERIC MODULATOR
- GABRB3 POSITIVE ALLOSTERIC MODULATOR
- GABRA4 POSITIVE ALLOSTERIC MODULATOR
- GABRG3 POSITIVE ALLOSTERIC MODULATOR
- GABRQ POSITIVE ALLOSTERIC MODULATOR
- GABRA3 POSITIVE ALLOSTERIC MODULATOR
- GABRP POSITIVE ALLOSTERIC MODULATOR
- GABRD POSITIVE ALLOSTERIC MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ALDH1A1
- APEX1
- ARSA
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP2E1
- CYP3A4
- DRD1
- EHMT2
- KDM4E
- LMNA
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anticonvulsants
- Central Nervous System Agents
- Central Nervous System Depressants
- GABA Agents
- GABA Modulators
- Hypnotics and Sedatives
- Neuroprotective Agents
- Neurotransmitter Agents
- Protective Agents
ATC classes
- N05C · HYPNOTICS AND SEDATIVES
Cross-references
Synonyms
- chlormethiazole
- chlorethiazol
- chlorethiazole
- chlormethiazol
- clomethiazolum
- distraneurin
- emineurina
- chlormethiazole hydrochloride
- chlormethiazole HCl
- clomethiazole edisilate
- Clometiazol
- Chlormethiazole
- Distraneurine
- Heminevrin
- 5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE
- Distraneurin
- Emineurina
- Clomethiazolum
- Chlormethiazol
- Chlorethiazol
- Chlorethiazole
- Somnevrin
- Clometiazole
- Clomethiazol
- 5-(2-Chloroethyl)-4-methyl-1,3-thiazole
- Thiazole, 5-(2-chloroethyl)-4-methyl-
- Clometiazolo [DCIT]
- Chloro-S.C.T.Z.
- C6H8ClNS
- UNII-0C5DBZ19HV
- Clometiazol [INN-Spanish]
- Clomethiazolum [INN-Latin]
- WY 1485
- Clomethiazole [INN]
- SCTZ [as edisylate]
- EINECS 208-565-7
- 4-Methyl-5-(beta-chloroethyl)thiazole
- BRN 0114244
Look up CLOMETHIAZOLE in the interactive SynDRA portal →