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GLIPIZIDE
SynDRA canonical compound SYN0003512 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ABCC8 |
|---|
| Mechanism of action | Sulfonylurea |
|---|
| Indication | diabetes mellitus | hyperglycemia |
|---|
| Disease area | endocrinology |
|---|
All known targets
- ABCC8
- KCNJ11
- KCNJ10
- PPARG
Mechanisms of action (all sources)
- KCNJ11 BLOCKER
- Sulfonylurea receptor 1, Kir6.2 blocker
- ABCC8 BLOCKER
- KCNJ10 BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD2
- CNR1
- CYP3A4
- MAPT
- LMNA
- MAOA
- MAPK1
- MAPK14
- MAPK3
- MC3R
- NPY1R
- MC4R
- MC5R
- MLNR
- MMP1
- MMP9
- LCK
- ABCC2
- KCNH2
- HTR7
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GMNN
- GIPR
- NFKB1
- NPY2R
- GCGR
- SLCO1B3
- SIGMAR1
- SLC29A1
- SLC6A2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Hypoglycemic Agents
- Sulfonylurea
ATC classes
- A10B · BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Cross-references
Synonyms
- GLIPIZIDE AND METFORMIN HYDROCHLORIDE
- GLUCOTROL
- GLUCOTROL XL
- Glucotrol
- METAGLIP
- glypidizine
- glidiazinamide
- K-4024
- K4024
- dipazide
- glibenese
- glipizid
- glucotrol
- glucozide
- glupizide
- glydiazinamide
- melizide
- napizide
- sucrazide
- Glipizida
- Glipizide slow release
- CP-28,720
- CP-28720
- NSC-759120
- Glibenese
- Glipizide component of metaglip
- Glucotrol xl
- Minodiab 2.5
- Minodiab 5
- Aldiab
- Digrin
- Dipazide
- Glibetin
- Glican
- Glide
- Glidiab
- Glidiazinamide
Reported adverse events
- Lactic acid
- Lactic acidosis
- Dizziness
- Leukopenia
- Porphyria
- Headache
- Hypertension
- Nausea
- Abdominal pain
- Musculoskeletal pain
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