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PROCYCLIDINE
SynDRA canonical compound SYN0003508 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | CHRM1 |
|---|
| Mechanism of action | acetylcholine receptor antagonist | antispasmodic |
|---|
| Indication | akathisia | dystonia | parkinsonism | Parkinson's Disease |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- CHRM1
- CHRM5
- CHRM2
- CHRM3
- CHRM4
- GRIN1
- GRIN2A
- GRIN2B
- GRIN2C
- GRIN2D
- GRIN3A
- GRIN3B
Mechanisms of action (all sources)
- CHRM1 ANTAGONIST
- Muscarinic acetylcholine receptor M1 antagonist
- acetylcholine receptor antagonist
- CHRM5 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ABCC2
- ADORA1
- MAOA
- MC3R
- MC4R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- SMAD3
- SMPD1
- TBXA2R
- HTR3A
- HTR2C
- HTR2B
- BDKRB2
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABCB6
- ACM4
- ACM5
- CP2D6
- CP3A7
- GLI3
- KCMB2
- KCMB4
- MDR1
- RARA
Drug classes
- Cholinergic Antagonists
- Anticholinergic
- Anti-Dyskinesia Agents
- Antiparkinson Agents
- Central Nervous System Agents
- Cholinergic Agents
- Muscarinic Antagonists
- Neurotransmitter Agents
- antispasmodic
ATC classes
- N04A · ANTICHOLINERGIC AGENTS
Cross-references
Synonyms
- KEMADRIN
- kemadrine
- tricoloid
- tricyclamol
- procyclidine hydrochloride
- procyclidine HCl
- Prociclidina
- Elorine
- Kemadrine
- Lergine
- Tricoloid
- Vagosin
- NSC-169103
- Arpicolin
- Kemadrin
- Metanin
- Osnervan
- Procidlidina
- Procyclid
- Procyclidinum
- Procyklidin
- Prosyklidin
- Spamol
- Triciclidina
- Triciloid
- Tricyclamol
- Prociclidina [INN-Spanish]
- Procyclidine (INN)
- Procyclidine [INN:BAN]
- Procyclidinum [INN-Latin]
- C6QE1Q1TKR
- NSC 169103
- 1-PYRROLIDINEPROPANOL, alpha-CYCLOHEXYL-alpha-PHENYL-
- CHEBI:8448
- (+-)-Procyclidine
- RefChem:868549
- DTXCID603515
- N04AA04
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