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VALSARTAN
SynDRA canonical compound SYN0003494 — structure-anchored drug synonym record
| Clinical phase | Launched |
| Approval status | Approved · Rx/OTC |
| Primary target(s) | AGTR1 |
| Mechanism of action | Angiotensin receptor antagonist |
| Indication | congestive heart failure | hypertension |
| Disease area | cardiology |
All known targets
Mechanisms of action (all sources)
- Angiotensin receptor antagonist
- AGTR1 ANTAGONIST
- Type-1 angiotensin II receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AGTR2
- MME
- NEIL2
- MUTYH
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MBD4
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LTB4R2
- ABCB11
- LCK
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HRH2
- HRH1
- HMGCR
- HDAC6
- GPR35
- GPR119
- GLP1R
- NEIL1
- NPY1R
- FPR2
- S1PR1
- TDG
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO2B1
- SLCO1B3
Drug classes
- Angiotensin 2 Receptor Antagonists
- Angiotensin 2 Receptor Blocker
- Angiotensin II Type 1 Receptor Blockers
- Angiotensin Receptor Antagonists
- Antihypertensive Agents
- Cardiovascular Agents
ATC classes
- C09C · ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), PLAIN
- ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), COMBINATIONS
- LIPID MODIFYING AGENTS, COMBINATIONS
Cross-references
Synonyms
- AMLODIPINE BESYLATE AND VALSARTAN
- AMLODIPINE BESYLATE, VALSARTAN AND HYDROCHLOROTHIAZIDE
- BYVALSON
- DIOVAN
- DIOVAN HCT
- Diovan
- ENTRESTO
- ENTRESTO SPRINKLE
- EXFORGE
- EXFORGE HCT
- Entresto
- Exforge
- diovan
- cardopan
- valsartanin
- CGP-48933
- NSC-758927
- Prexxartan
- Valsartan component of agsav301
- Valsartan component of byvalson
- Valsartan component of copalia
- Valsartan component of copalia-hct
- Valsartan component of dafiro
- Valsartan component of dafiro-hct
- Valsartan component of diovan hct
- Valsartan component of entresto
- Valsartan component of exforge
- Valsartan component of exforge hct
- Valsartan component of imprida
- Valsartan component of imprida-hct
- Valsartan component of valturna
- Tareg
- Provas
- L-Valsartan
- UNII-80M03YXJ7I
- N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
- CHEMBL1069
- 80M03YXJ7I
Reported adverse events
- Hypotension
- Hypersensitivity
- Alopecia
- Angioedema
- Vasculitis
- Dizziness
- Cough
- Neutropenia
- Arthralgia
- Rhabdomyolysis
- Fatigue
- Rash
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