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LICARBAZEPINE
SynDRA canonical compound SYN0003492 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Primary target(s) | SCN5A |
|---|
| Mechanism of action | Voltage-gated sodium channel blocker |
|---|
All known targets
- SCN5A
- SCN1A
- SCN3A
- SCN4A
- SCN7A
- SCN2A
- SCN9A
- SCN11A
- SCN8A
- SCN10A
- CYP2C19
- CYP3A4
Mechanisms of action (all sources)
- Voltage-gated sodium channel blocker
- Sodium channel blocker
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Drug classes
- Anticonvulsants
- Cardiovascular Agents
- Central Nervous System Agents
- Cytochrome P-450 CYP3A Inducers
- Membrane Transport Modulators
- Metabolic Side Effects of Drugs and Substances
- Sodium Channel Blockers
- Voltage-Gated Sodium Channel Blockers
- Anti-epileptic Agent
ATC classes
Cross-references
Synonyms
- Licarbazepina
- 10-hydroxy-carbamazepine
- GP-47779
- (-)-10,11-Dihydro-10-hydroxy-5H-dibenz(b,f)azepine-5-carboxamide
- 10,11-Dihydro-10-hydroxy-5H-dibenz(b,f)azepine-5-carboxamide
- 10,11-Dihydro-10-hydroxycarbamazepine
- 10-HYDROXY-CARBAMAZEPINE
- 10-Hydroxy-10,11-dihydro-5H-dibenz(b,f)azepine-5-carboxamide
- 10-Hydroxy-10,11-dihydrocarbamazepine
- 10-Hydroxycarbamazepine
- 10-Hydroxycarbazepine
- 10-OH-Carbazepine
- 5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide
- licarbazepina
- XFX1A5KJ3V
- CHEBI:701
- licarbazepinum
- RefChem:153361
- DTXCID70813886
- Licarbazepine [INN]
- MFCD00871817
- BIA 2-005
- UNII-XFX1A5KJ3V
- Licarbazepine (Standard)
- Epitope ID:423618
- SCHEMBL420263
- LICARBAZEPINE [WHO-DD]
- orb1299489
- orb3141229
- SCHEMBL12356854
- SCHEMBL29802374
- HMS3412J19
- HMS3676J19
- MSK10748
- BDBM50330859
- AKOS016011140
- AB92454
- FD21950
Reported adverse events
- Hypersensitivity
- Stevens-Johnson syndrome
- Somnolence
- Angioedema
- Asthenia
- Ataxia
- Diplopia
- Fatigue
- Rash
- Vertigo
- Vomiting
- Acne
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