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GABEXATE
SynDRA canonical compound SYN0003489 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | PRSS1 |
|---|
| Mechanism of action | Serine protease inhibitor |
|---|
| Indication | pancreatitis |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- TPSAB1
- PRSS1
- Aoc3
- F10
- F12
- F2
- HPN
- KLKB1
- PLAT
- PLAU
- PLG
- SLC22A2
Mechanisms of action (all sources)
- Serine protease inhibitor
- TPSAB1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TMPRSS2
- ESR1
- SLC6A2
- CHRM2
- POLI
- KLK7
- MAOA
- OPRM1
- PDE3A
- PDE4A
- PGR
- PTGS1
- KCNH2
- PTH1R
- SAMHD1
- SLC6A3
- SLC6A4
- TBXA2R
- TDP1
- KDR
- ACHE
- IDH1
- ADORA3
- ADRA1A
- ADRA2A
- ALOX15B
- AR
- CHRM1
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- DRD1
- DRD3
- HDAC6
- HRH3
- HTR1A
- HTR2B
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- CP1A2
- CP2D6
- HDAC3
- NSD2
- TRYB1
Drug classes
- Anticoagulants
- Enzyme Inhibitors
- Hematologic Agents
- Protease Inhibitors
- Serine Proteinase Inhibitors
Cross-references
Synonyms
- gabexate mesilate
- gabexate mesylate
- Gabexato
- Gabexate [INN]
- Gabexatum [INN-Latin]
- Gabexato [INN-Spanish]
- UNII-4V7M9137X9
- CHEMBL87563
- C16H23N3O4
- Gabexate (INN)
- 4V7M9137X9
- Ethyl p-hydroxybenzoate 6-guanidinohexanoate
- ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate
- Gabexatum
- Benzoic acid, 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-, ethyl ester
- p-carbethoxyphenyl e-guanidinocaproate
- AC1L1FYH
- Prestwick3_001008
- Prestwick2_001008
- Prestwick0_001008
- Prestwick1_001008
- BSPBio_001135
- SCHEMBL446024
- SPBio_003016
- GTPL7863
- ethyl 4-(6-(diaminomethylideneamino)hexanoyloxy)benzoate
- Mesilate, Gabexate
- Mesylate, Gabexate
- RefChem:142027
- Methanesulfonate, Gabexate
- Monomethanesulfonate, Gabexate
- DTXCID2028195
- Gabexate Monomethanesulfonate, 14C Labeled Cpd
- ethyl 4-((6-carbamimidamidohexanoyl)oxy)benzoate
- Ethyl 4-((6-guanidinohexanoyl)oxy)benzoate
- ethyl 4-({6-[(diaminomethylidene)amino]hexanoyl}oxy)benzoate
- GABEXATE [JAN]
- GABEXATE [MI]
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