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METHYSERGIDE
SynDRA canonical compound SYN0003485 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | HTR7 |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
| Indication | headache |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- HTR2C
- HTR2B
- HTR1B
- HTR2A
- HTR1F
- HTR1E
- HTR7
- HTR1D
- HTR5A
- HTR6
- HTR1A
- Htr5a
Mechanisms of action (all sources)
- Serotonin receptor antagonist
- HTR2B ANTAGONIST
- Serotonin 2b (5-HT2b) receptor antagonist
- HTR1A PARTIAL AGONIST
- Serotonin 1a (5-HT1a) receptor partial agonist
- HTR2C ANTAGONIST
- Serotonin 2c (5-HT2c) receptor antagonist
- HTR1B ANTAGONIST
- HTR1D ANTAGONIST
- HTR1E ANTAGONIST
- HTR1F ANTAGONIST
- HTR2A ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA1A
- HRH2
- ESR2
- ABCB11
- MLNR
- MAPT
- MBNL1
- MC3R
- MC4R
- MC5R
- MMP1
- MAPK14
- MMP9
- NPY1R
- NPY2R
- NR3C1
- NTSR1
- MAPK3
- MAOA
- MAPK1
- OPRK1
- LCK
- KMT2A
- KDM4E
- KCNH2
- KAT2A
- IDH1
- HTR3A
- HRH3
- HPGD
- HMGCR
- HIF1A
- HDAC6
- OPRD1
- OPRM1
- GLS
- PABPC1
- VIPR1
- VDR
- USP2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT1B
- GNMT
- HCRTR1
- HNMT
- KSYK
- M3K3
- M4K2
- MYC
- NNMT
- NTM1A
- PABP1
- PADI4
- PNMT
- PPCEL
- PRMT1
- PSIP1
- SYK
- GSTO1
- GAMT
- 5HT1D
- G3P
- 5HT1E
- 5HT1F
- 5HT2A
- 5HT5A
- 5HT6R
- 5HT7R
- ACES
- AHR
- APAF
- ATRX
- B2CL1
- CIB1
- COMT
- CP2D6
- CP3A7
- TYDP2
Drug classes
- Cardiovascular Agents
- Neurotransmitter Agents
- Serotonin Agents
- Serotonin Antagonists
- Vasoconstrictor Agents
ATC classes
- N02C · ANTIMIGRAINE PREPARATIONS
Cross-references
Synonyms
- SANSERT
- deseril
- methysergid
- methysergide maleate
- Metisergida
- Deseril
- Desernil
- Desernyl
- Deseryl
- Desril
- Dimethylergometrin
- Methylmethylergonovine
- Methysergid
- Methysergidum
- Metisergide
- Metisergido
- Sansert
- Methyllysergic acid butanolamide
- Metisergide [DCIT]
- UML-491
- Deseril (TN)
- Methysergidum [INN-Latin]
- Metisergido [INN-Spanish]
- Sansert (TN)
- Methysergide (USAN/INN)
- Methysergide [USAN:INN:BAN]
- N-(alpha-(Hydroxymethyl)propyl)-1-methyl-dextro-lysergamide
- N-(1-(Hydroxymethyl)propyl)-1-methyl-dextro-(+)-lysergamide
- (+)-N-(1-(Hydroxymethyl)propyl)-1-methyl-D-lysergamide
- 1-Methyl-D-lysergic acid butanolamide
- 1-Methylmethylergonovine
- metisergida
- XZA9HY6Z98
- DTXCID703307
- Maleate, Methysergide
- Dimaleate, Methysergide
- RefChem:818760
- UML491
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