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HYDROXYPROGESTERONE
SynDRA canonical compound SYN0003477 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | PGR |
|---|
| Mechanism of action | Progesterone receptor agonist |
|---|
| Indication | spontaneous preterm birth |
|---|
| Disease area | obstetrics/gynecology |
|---|
All known targets
- PGR
- AR
- CYP1A2
- CYP2B6
- CYP3A5
- ESR1
- ESR2
- NR1H4
- NR1I2
- NR3C1
- SLC6A3
- ADORA3
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- OPRK1
- NR3C1
- NPY2R
- NPY1R
- NFE2L2
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPT
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KCNH2
- KAT2A
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HSD17B7
- HRH2
- HRH1
- OPRD1
- OPRM1
- ADORA1
- PDE5A
- UGT2B7
- UGT2B17
- UGT1A8
- UGT1A7
- UGT1A10
- TDP1
- TBXAS1
- TARDBP
- TACR2
Drug classes
- Estrogen Antagonists
- Hormone Antagonists
- Hormones
- Progestins
- Progestin
ATC classes
- G03D · PROGESTOGENS
- PROGESTOGENS AND ESTROGENS IN COMBINATION
Cross-references
Synonyms
- Delalutin (TN)
- Proluton depot (TN)
- NSC 15468
- Pregn-4-ene-3,20-dione, 17-hydroxy-
- U 3096
- Prodix
- Prodox
- Gestageno gador
- Gestageno
- Hidroxiprogesterona
- Hydroxyprogesteronum
- Pregn-4-ene-3,20-dione-17-ol
- delta(4)-Pregnene-17alpha-ol-3,20-dione
- Idrossiprogesterone
- alpha Hydroxy progesterone
- CHEBI:17252
- DTXCID4020747
- RefChem:55376
- Setaderm
- Oxiprogesteronum
- Idrossiprogesterone [DCIT]
- Hydroxyprogesteronum [INN-Latin]
- Hidroxiprogesterona [INN-Spanish]
- MFCD00003659
- HSDB 3343
- 4-Pregnen-17a-ol-3,20-dione
- MLS000028453
- MLS001076300
- 4-Pregnen-17alpha-ol-3,20-dione
- Delta4-Pregnen-17alpha-ol-3,20-dione
- NCGC00093949-03
- alpha-17Hydroxypregn-4-ene-3,20-dione
- SMR000058349
- Hydroxyprogesterone (INN)
- (9beta)-17-Hydroxypregn-4-Ene-3,20-Dione
- HYDROXYPROGESTERONE [INN]
- CAS-68-96-2
Reported adverse events
- Cervical incompetence
- Headache
- Infection
- Injection site pain
- Injection site pruritus
- Nausea
- Oligohydramnios
- Pregnancy
- Pruritus
- Rash
- Stillbirth
- Urinary tract infection
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