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TOLNAFTATE
SynDRA canonical compound SYN0003419 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Mechanism of action | fungal squalene epoxidase inhibitor |
|---|
| Indication | tinea corporis | tinea pedis |
|---|
| Disease area | infectious disease |
|---|
All known targets
- CYP2C19
- CYP51A1
- HTR2B
- SQLE
Mechanisms of action (all sources)
- fungal squalene epoxidase inhibitor
- SQLE INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD1
- DRD3
- NR1I2
- HRH1
- MAPK1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPT
- MAPK3
- MAPK14
- MAOA
- HRH2
- GMNN
- LMNA
- HMGCR
- LCK
- KDM4A
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2A
- HTR1A
- ABCB11
- NR3C1
- OPRD1
- SIGMAR1
- USP1
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ANDR
- CP1A2
- CP2C9
- CP2CJ
- CP3A4
- CP3A7
- ESRRA
- GLI3
- NF2L2
- NSD2
- PRGR
- RAPGEF3
- RARA
- RPGF3
- RXFP1
Drug classes
- Anti-Infective Agents
- Antifungal Agents
ATC classes
- D01A · ANTIFUNGALS FOR TOPICAL USE
Cross-references
Synonyms
- Absorbine
- Fungifoam
- Molecular AF
- Ony-Clear
- Proclearz
- Tinactin
- Tinaderm
- Zeasorb
- tolnaphthate
- tolsanil
- tonoftal
- Tolnaftato
- Separin
- NSC-233648
- SCH-10144
- Mycil
- Timoped
- Tinaderm plus
- Tineafax
- Aftate
- Breezee
- Chinofungin
- Dermoxin
- Dungistop
- Focusan
- Fungistop
- Genaspor
- Micoisdin
- Phytoderm
- Pitrex
- Sorgoa
- Sporiline
- Tinatox
- Tinavet
- Ting
- Tniaderm
- Tolnaftatum
- Tolnaphthate
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