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TIAPRIDE
SynDRA canonical compound SYN0003411 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | DRD3 |
|---|
| Mechanism of action | Dopamine receptor antagonist |
|---|
| Indication | abstinence from alcohol | dyskinesia | psychosis |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- DRD2
- DRD3
- ADRA2A
- DRD4
- SCN10A
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- DRD3 ANTAGONIST
- Dopamine D3 receptor antagonist
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- SCN10A INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ACHE
- MAPK1
- NR1I2
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MBNL1
- MAPK3
- MAPK14
- MAOA
- OPRD1
- LMNA
- LCK
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- NR3C1
- OPRK1
- ADORA1
- SLC29A1
- USP1
- TSHR
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- STAT6
- SLCO1B3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Antipsychotic Agents
- Central Nervous System Agents
- Central Nervous System Depressants
- Dopamine Agents
- Dopamine Antagonists
- Neurotransmitter Agents
- Psychotropic Drugs
- Tranquilizing Agents
ATC classes
Cross-references
Synonyms
- tiapridal
- tiapride monohydrochloride
- tiapride hydrochloride
- thiapride
- tiaprizal
- tiapride HCl
- Tiaprida
- NSC-758225
- Thiapride
- Tiapridal
- N-(2-(Diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)benzamide
- Tiapridum [INN-Latin]
- Tiaprida [INN-Spanish]
- UNII-LAH70H9JPH
- FLO 1347
- Tiapride [INN:BAN:DCF]
- Tiapride HCl
- EINECS 256-907-9
- LAH70H9JPH
- BRN 2390588
- JTVPZMFULRWINT-UHFFFAOYSA-N
- BENZAMIDE, N-(2-(DIETHYLAMINO)ETHYL)-2-METHOXY-5-(METHYLSULFONYL)-
- N-(2-(Diethylamino)ethyl)-5-(methylsulfonyl)-o-anisamide
- Tiapridum
- Benzamide, N-[2-(diethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)-
- NCGC00015996-02
- SPI-860
- NSC 758225
- RefChem:898104
- DTXCID903664
- N05AL03
- Thiapride; Tiapride
- Tiapride (INN)
- TIAPRIDE [INN]
- CAS-51012-33-0
- Tiapridal (TN)
- MFCD00242730
- Spectrum_001354
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