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LATANOPROST
SynDRA canonical compound SYN0003403 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PTGFR |
|---|
| Mechanism of action | prostanoid receptor agonist |
|---|
| Indication | glaucoma | ocular hypertension |
|---|
| Disease area | ophthalmology |
|---|
All known targets
- PTGFR
- PTGER1
- PTGER3
- GUCY1A1
Mechanisms of action (all sources)
- PTGFR AGONIST
- Prostanoid FP receptor agonist
- prostanoid receptor agonist
- PTGFR FULL AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- NR3C1
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- KDM4E
- MAOA
- MAPK1
- MAPT
- MC3R
- MLNR
- NPY1R
- NR1I2
- OPRD1
- HTR1A
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PPARG
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO2A1
- HTR2A
- HRH3
- ADORA1
- CCKAR
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- KCMA1
- KCMB1
- KCMB2
- KCMB4
- LRC26
Drug classes
- Prostaglandin Analog
- Ophthalmic Solutions
- Pharmaceutical Solutions
ATC classes
- S01E · ANTIGLAUCOMA PREPARATIONS AND MIOTICS
Cross-references
Synonyms
- IYUZEH
- Iyuzeh
- ROCKLATAN
- Rocklatan
- XALATAN
- XELPROS
- Xalatan
- Xelpros
- roclanda
- xalatan
- (15R)-Latanoprost
- PhXA41
- Latanoprost (isopropyl ester)
- PHXA-41
- PHXA41
- T-2345
- T2345
- XA-41
- XA41
- Catiolanze
- Latanoprost component of rocklatan
- Latanoprost component of xalacom
- Monopost
- Catioprost
- Latanoprost free acid
- L1167_SIGMA
- AR-202
- Nova-21027
- Xalatan (TN)
- Latanoprost (JAN/USAN/INN)
- PhXA34 [as 15(R,S)-isomer]
- PhXA 41
- XA 41
- latanoprost (isopropyl ester)
- Latanoprost, (+/-)-
- 6Z5B6HVF6O
- 8S5FB3XXG8
Reported adverse events
- Eyelash changes
- Asthma
- Rash
- Nausea
- Chest pain
- Dizziness
- Dry eye
- Myalgia
- Photophobia
- Eye pain
- Foreign body
- Punctate keratitis
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