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FANANSERIN
SynDRA canonical compound SYN0003398 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | HTR2A |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- Serotonin receptor antagonist
- HTR2A ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD2
- SLC6A3
- HTR2B
- HTR6
- HTR7
- HTR1A
- KCNH2
- ADRA1A
- HRH1
- OPRK1
- DRD3
- HTR5A
- DRD1
- SIGMAR1
- SLC6A2
- HTR2C
- SLC6A4
- ADRA1B
- ADRA1D
- TMEM97
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB2
- NEIL1
- UNG
- MPG
- NEIL2
- SMUG1
- NTHL1
- OGG1
- OPRD1
- TSPO
- OPRM1
- S1PR1
- TDP1
- TDG
- ADGRF1
- HRH3
- HTR3A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ANDR
- CP1A2
- CP2CJ
- CP2D6
- CP3A7
- ESR1
- ESRRA
- NF2L2
- NR1I2
- PRGR
- TP53
Drug classes
- Antipsychotic Agents
- Dopamine Agonists
- Serotonin Antagonists
Cross-references
Synonyms
- Fananserine
- Fananserina
- RP-62203
- RP62203
- Fananserin [USAN:INN]
- UNII-38QJ762ET6
- CHEMBL83894
- C23H24FN3O2S
- VGIGHGMPMUCLIQ-UHFFFAOYSA-N
- 38QJ762ET6
- NCGC00167808-01
- DSSTox_RID_81871
- DSSTox_CID_26743
- 2-(3-(4-(p-Fluorophenyl)-1-piperazinyl)propyl)-2H-naphth(1,8-cd)isothiazole 1,1-dioxide
- 2H-Naphth(1,8-cd)isothiazole, 2-(3-(4-(4-fluorophenyl)-1-piperazinyl)propyl)-, 1,1-dioxide
- DSSTox_GSID_46743
- [3H]fananserin
- CAS-127625-29-0
- Fananserin (USAN/INN)
- [3H]RP62203
- [3H]RP-62203
- AC1L1TX5
- 2-(3-(4-(4-fluorophenyl)-1-piperazinyl)propyl)-2H-naphth(1,8-cd)isothiazole 1,1-dioxide
- FANANSERINE
- DTXCID6026743
- fananserinum
- RefChem:921463
- Fananserin [INN]
- FANANSERIN [USAN]
- SCHEMBL340722
- ChEMBL_131689
- GTPL3229
- GTPL5434
- orb1308312
- CHEBI:92159
- HMS3269J05
- HMS3413N09
- HMS3677N09
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