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SPIRAMIDE
SynDRA canonical compound SYN0003369 — structure-anchored drug synonym record
| Primary target(s) | HTR2A |
|---|
| Mechanism of action | Serotonin receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- Serotonin receptor antagonist
- HTR2A ANTAGONIST
- HTR2B ANTAGONIST
- HTR2C ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HRH1
- SLC6A3
- HTR1D
- HTR7
- ADRA1A
- GPR183
- NR1I2
- DRD4
- DRD3
- DRD2
- OPRK1
- OPRM1
- SIGMAR1
- CHRM5
- HTR6
- SLC6A4
- ADRA1B
- ADRA1D
- TMEM97
- ADRA2A
- ADRB2
- ADRB1
- ADRA2B
- ADRA2C
- NEIL2
- MAPT
- MBD4
- MPG
- MUTYH
- NEIL1
- NTHL1
- SMUG1
- OGG1
- UNG
- OPRD1
- TDP1
- HTR5A
- S1PR1
- TDG
- SLC6A2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- 5HT2B
- TRFR
- SMAD3
- SMAD2
- RARA
- PRGR
- NSD2
- NF2L2
- KCNH2
- JUN
- GNRHR
- ESR2
- ESR1
- CP3A7
- CP2D6
- CP19A
- ATF6
- ANDR
- ACM1
- 5HT2C
- TRHR
Cross-references
Synonyms
- Espiramida
- R-5808
- AMI-193
- Spiramidum
- CHEBI:64207
- RefChem:184726
- Spiramide [INN]
- Fluroxyspiramine
- NCGC00024633-02
- AMI 193;AMI-193;AMI193
- DTXCID4022579
- CAS-510-74-7
- Spiramidum [INN-Latin]
- Espiramida [INN-Spanish]
- UNII-471LF4O004
- Tocris-0524
- Biomol-NT_000039
- Biomol-NT_000087
- GTPL175
- BPBio1_001087
- BPBio1_001259
- orb1306174
- SCHEMBL2110721
- BDBM86525
- TQP0728
- FJUKDAZEABGEIH-UHFFFAOYSA-N
- EX-A7239
- Tox21_110914
- CAS_77445
- MFCD00673878
- NSC_77445
- AKOS024458544
- Tox21_110914_1
- EBC-605270
- GS-9308
- NCGC00024633-01
- NCGC00024633-03
- NCGC00024633-04
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